Adherence to Protease Inhibitor Therapy and Outcomes in Patients with HIV Infection
- D. Paterson, S. Swindells, N. Singh
- MedicineAnnals of Internal Medicine
- 4 July 2000
Given the critical importance of adherence to therapy to patient outcome, secondary prevention of HIV infection, and willingness of providers to prescribe therapy, this prospectively investigated the association between protease inhibitor adherence and patient outcome and factors related to adherence.
Pediatric Visceral Leishmaniasis in Western Sicily, Italy: A Retrospective Analysis of 111 Cases
- A. Cascio, C. Colomba, S. Antinori, M. Orobello, D. Paterson, L. Titone
- MedicineEuropean Journal of Clinical Microbiology and…
- 19 February 2002
The clinical and epidemiological characteristics of 111 consecutive cases of visceral leishmaniasis identified from 1980 to 2000 in a Sicilian pediatric hospital were analyzed retrospectively and the use of the term "Mediterranean visceral leishingmaniasis", rather than theterm "kala-azar", is proposed for cases observed in the Mediterranean area.
Effectiveness of H1N1/09 monovalent and trivalent influenza vaccines against hospitalization with laboratory-confirmed H1N1/09 influenza in Australia: a test-negative case control study.
- A. Cheng, T. Kotsimbos, P. Kelly
- Medicine, BiologyVaccine
- 6 October 2011
Influenza Vaccine Effectiveness against Hospitalisation with Confirmed Influenza in the 2010–11 Seasons: A Test-negative Observational Study
- A. Cheng, Mark Holmes, T. Kotsimbos
- Medicine, Political SciencePLoS ONE
- 16 July 2013
Immunisation programs are designed to reduce serious morbidity and mortality from influenza, but most evidence supporting the effectiveness of this intervention has focused on disease in the…
Clinical Characteristics, Etiology, and Initial Management Strategy of Newly Diagnosed Periprosthetic Joint Infection: A Multicenter, Prospective Observational Cohort Study of 783 Patients
- L. Manning, S. Metcalf, Josh Davis
- MedicineOpen Forum Infectious Diseases
- 1 May 2020
Late acute infection was the most common mode of presentation and management was heterogeneous, reflecting the poor evidence base and the need for randomized controlled trials.
The Australasian COVID-19 Trial (ASCOT) to assess clinical outcomes in hospitalised patients with SARS-CoV-2 infection (COVID-19) treated with lopinavir/ritonavir and/or hydroxychloroquine compared…
- J. Denholm, Joshua S. Davis, S. Slow
- MedicineTrials
- 14 July 2020
To determine if lopinavir/ritonavir +/- hydroxychloroquine will reduce the proportion of participants who survive without requiring ventilatory support, 15 days after enrolment, in adult participants with non-critically ill SARS-CoV-2 infection, an investigator-initiated, multi-centre, open-label, randomised controlled trial.
Lopinavir-ritonavir and hydroxychloroquine for critically ill patients with COVID-19: REMAP-CAP randomized controlled trial
Among critically ill patients with COVID-19, lopinavir-ritonavir, hydroxychloroquine, or combination therapy worsened outcomes compared to no antiviral therapy, and the three interventions reduced hospital survival compared with control.
Transrectal versus transperineal prostate biopsy under intravenous anaesthesia: a clinical, microbiological and cost analysis of 2048 cases over 11 years at a tertiary institution
- M. Roberts, A. Macdonald, J. Yaxley
- MedicineProstate Cancer and Prostatic Diseases
- 5 August 2020
TR biopsy resulted in more infectious complications and hospital admissions than TP biopsy for similar rates of re-presentation and urinary retention, and use in conjunction with mpMRI provides an overall cost saving.
Multicentre randomised double-blind placebo controlled trial of combination vancomycin and cefazolin surgical antibiotic prophylaxis: the Australian surgical antibiotic prophylaxis (ASAP) trial
- T. Peel, Sarah Astbury, R. de Steiger
- MedicineBMJ Open
- 1 November 2019
This randomised, double-blind, parallel, superiority, placebo-controlled, phase 4 trial will compare the incidence of all surgical site infections, safety and cost-effectiveness of surgical prophylaxis with cefazolin plus vancomycin to that with cephalosporin plus placebo.
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