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Autonomic innervation and regulation of the immune system (1987–2007)
The primary pathway for the neural regulation of immune function is provided by the sympathetic nervous system (SNS) and its main neurotransmitter, norepinephrine (NE). Expand
Inhibition of Apoptosis in Chlamydia-infected Cells: Blockade of Mitochondrial Cytochrome c Release and Caspase Activation
A chlamydial antiapoptosis mechanism(s) is identified that will help define chlamYDial pathogenesis and may also provide information about the central mechanisms regulating host cell apoptosis. Expand
Neural and biochemical mediators of endotoxin and stress-induced c-fos expression in the rat brain
Prostaglandin synthesis, glutamate release, histamine receptors, and visceral afferents represent functional biochemical and neural pathways through which endotoxin activates c-fos protein in specific autonomic and neuroendocrine regulatory nuclei. Expand
Correction. Molecular cloning of a novel hyaluronan receptor that mediates tumor cell motility
A cDNA encoding a unique hyaluronan receptor has been molecularly cloned from a lambda GT11 3T3 cDNA expression library and is named RHAMM, an acronym for receptor for hyAluronan-mediated motility, which appears to be a new type of hyalonson receptor that is involved in cell locomotion. Expand
Cytokine-specific central monoamine alterations induced by interleukin-1, -2 and -6
These cytokines differentially altered neurochemical activity in brain regions that mediate neuroimmune interactions and that are influenced by physical and psychological stressors. Expand
Migration of bovine aortic smooth muscle cells after wounding injury. The role of hyaluronan and RHAMM.
Data demonstrate that RHAMM is necessary for the migration of smooth muscle cells and that expression and distribution of this receptor is tightly regulated following wounding of BASMC monolayers. Expand
Interactions between cancer cells and the endothelium in metastasis
The haematogenous phase of cancer metastasis facilitates the transport of metastatic cells within the blood and incorporates a sequence of interactions between circulating intravascular cancer cellsExpand
Interleukin-2 and -6 induce behavioral-activating effects in mice
It is suggested that these effects have adaptive significance and relevance to sickness behavior; however, pathological outcomes could develop should these cytokine-specific behavioral-activating effects be overproduced or dysregulated. Expand
Double-labeling of neuropeptide Y-immunoreactive neurons which project from the geniculate to the suprachiasmatic nuclei
It is demonstrated that many neuropeptide Y-immunoreactive neurons located in both the intergeniculate leaflet and in the external lamina of the anterior VLGN project to the SCN in hamsters. Expand
Differential induction of c-Fos immunoreactivity in hypothalamus and brain stem nuclei following central and peripheral administration of endotoxin
Testing the effects of ICV infusions of LPS or Ringer's solution on the induction of the proto-oncogene protein c-Fos in the brain as well as plasma levels of corticosterone and splenic concentrations of norepinephrine and VIP found that these levels were elevated post-ICV LPS. Expand