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Longitudinal cohort study on the effectiveness of lipid apheresis treatment to reduce high lipoprotein(a) levels and prevent major adverse coronary events
Background We investigated in a longitudinal, multicenter, cohort study whether combined lipid apheresis and lipid-lowering medication can reduce extremely high levels of lipoprotein(a) (Lp[a]) andExpand
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Soluble MICA in malignant diseases
The immunoreceptor NKG2D activates natural killer cells and costimulates CD8 T cells. The MHC class I–related MICA molecules are ligands of NKG2D and are expressed on malignant, but not on normal,Expand
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CYFRA 21‐1: A new marker in lung cancer
Background. It is known that cytokeratin 19 is particularly abundant in carcinoma of the lung.
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PROGNOSTIC VALUE OF INTERLEUKIN 6, PROCALCITONIN, AND C-REACTIVE PROTEIN LEVELS IN INTENSIVE CARE UNIT PATIENTS DURING FIRST INCREASE OF FEVER
ABSTRACT To investigate the prognostic value of interleukin 6 (IL-6), procalcitonin (PCT), and C-reactive protein (CRP) in critically ill patients during the first increase of fever, serum levelsExpand
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Variability of linezolid concentrations after standard dosing in critically ill patients: a prospective observational study
IntroductionSevere infections in intensive care patients show high morbidity and mortality rates. Linezolid is an antimicrobial drug frequently used in critically ill patients. Recent data indicatesExpand
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The diagnostic accuracy of two human epididymis protein 4 (HE4) testing systems in combination with CA125 in the differential diagnosis of ovarian masses
Abstract Background: Cancer antigen 125 (CA125) is the best known single tumor marker for ovarian cancer (OC). We investigated whether the additional information of the human epididymis protein 4Expand
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Methods for isolation of cell-free plasma DNA strongly affect DNA yield.
Extracellular nucleic acids are present in plasma, serum, and other body fluids and their analysis has gained increasing attention during recent years. Because of the small quantity and highlyExpand
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Prognostic role of methylated free circulating DNA in colorectal cancer
DNA hypermethylation is frequently found in colorectal cancer (CRC). Methylation of helicase‐like transcription factor (HLTF) and hyperplastic polyposis 1 (HPP1) are potential and carcinoembryonicExpand
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Clinical Relevance of Circulating Nucleosomes in Cancer
Nucleosomes, complexes of DNA and histone proteins, are released during cell death into the blood circulation. Elevated serum and plasma levels have been found in various forms of cancer, but also inExpand
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Preoperative CYFRA 21-1 and CEA as Prognostic Factors in Patients with Stage I Non-Small Cell Lung Cancer
Objective: To validate the prognostic value of preoperative levels of CYFRA 21-1, CEA and the corresponding tumor marker index (TMI) in patients with stage I non-small cell lung cancer (NSCLC).Expand
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