How common is attention-deficit/hyperactivity disorder? Incidence in a population-based birth cohort in Rochester, Minn.
- W. Barbaresi, S. Katusic, S. Jacobsen
- Medicine, PsychologyArchives of Pediatrics & Adolescent Medicine
- 1 March 2002
These results provide insight into the apparent discrepancies in estimates of the occurrence of AD/HD, with less stringent criteria resulting in higher cumulative incidence.
A feeding scale for research and clinical practice to assess mother—infant interactions in the first three years of life
The Feeding Scale provides a reliable rating of mother-infant/toddler interactions during a 20-minute feeding in a laboratory setting and discriminates between infants with and without feeding disorders as well as three diagnostic categories of feeding-disordered infants.
Depression, apolipoprotein E genotype, and the incidence of mild cognitive impairment: a prospective cohort study.
Cognitively normal elderly individuals who develop depression are at increased risk of subsequent MCI and a synergistic interaction between depression and apolipoprotein E genotype is found.
Evolution and revolution in child psychiatry: ADHD as a disorder of adaptation.
- P. Jensen, D. Mrazek, T. Shapiro
- PsychologyJournal of the American Academy of Child and…
- 1 December 1997
The authors examine attention-deficit/hyperactivity disorder (ADHD) in relation to evolutionary theories of psychology and biology and clarify the potentially adaptive nature of characteristics of inattention, impulsivity, and motoric hyperactivity, depending on the nature of child's environments.
SLC6A4 variation and citalopram response
It is suggested that multiple variations in the SLC6A4 gene are associated with remission in white non‐Hispanic depressed adults treated with citalopram, and the mechanism of action of these variants remains to be determined.
Problem behavior in early and middle childhood: an initial behavior genetic analysis.
- S. Schmitz, D. Fulker, D. Mrazek
- Psychology, MedicineJournal of Child Psychology and Psychiatry and…
- 1 November 1995
Results suggested that shared environmental influences may be more important in early childhood than in middle childhood, while the reverse holds for genetic influences.
A review of the clinical, economic, and societal burden of treatment-resistant depression: 1996-2013.
- D. Mrazek, J. Hornberger, C. Altar, Irina Degtiar
- Medicine, PsychologyPsychiatric Services
- 1 August 2014
Treatment-resistant depression may present an annual added societal cost of $29-$48 billion, pushing up the total societal costs of major depression by as much as $106-$118 billion, and underscore the need for research on the mechanisms of depression, new therapeutic targets, existing and new treatment combinations, and tests to improve the efficacy of and adherence to treatments for treatment- resistant depression.
Onset and persistence of childhood asthma: predictors from infancy.
- M. Klinnert, H. Nelson, M. Price, A. Adinoff, D. Leung, D. Mrazek
- Medicine, PsychologyPediatrics
- 1 October 2001
3 proved to have significant univariate relationships with asthma between ages 6 and 8: elevated IgE levels measured when the children were 6 months of age, global ratings of parenting difficulties measured when infants were 3 weeks old, and higher numbers of respiratory infections in the first year of life.
Psychiatric pharmacogenomic testing in clinical practice
- D. Mrazek
- Medicine, BiologyDialogues in Clinical Neuroscience
- 1 March 2010
Genotyping the highly variable cytochrome P 4 5 0 2D 6 gene now provides clinicians with the opportunity to identify both poor metabolizers and ultrarapid metabolizers of 2D6 substrate medications.
CYP2C19 variation and citalopram response
- D. Mrazek, J. Biernacka, R. Weinshilboum
- Medicine, PsychologyPharmacogenetics & Genomics
- 1 January 2011
Variations in CYP2C19 were associated with tolerance and remission in a large sample of White non-Hispanic patients treated with citalopram, despite several limitations including the lack of serum drug levels.