• Publications
  • Influence
Frequencies of chromosomal aberrations in pesticide sprayers working in plastic green houses.
The frequency of chromosome aberrations was studied in peripheral blood lymphocytes of 29 workers occupationally exposed to a mixture of pesticides and in 14 age- and sex-matched healthy controls.Expand
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Genotoxic and cytotoxic effects of different types of dental cement on normal cultured human lymphocytes.
In this study we have investigated the genotoxic and cytotoxic effects of eluates derived from different types of commercially available dental cements, including glass ionomer cements (GICs) (KetacExpand
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Sister chromatid exchange assay as a predictor of tumor chemoresponse.
  • D. Mourelatos
  • Medicine
  • Mutation research. Genetic toxicology and…
  • 1 June 2016
Sister Chromatid Exchanges (SCEs) are known to enhance as a consequence of exposure to various mutagenic agents and appear to indicate DNA damaging effects and/or subsequent repair by homologousExpand
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Enhancement of cytogenetic damage and of antineoplastic effect by caffeine in Ehrlich ascites tumor cells treated with cyclophosphamide in vivo.
Enhanced cytogenetic damage by cyclophosphamide (CP) was observed when Ehrlich ascites tumor cells were exposed in vivo to nontoxic concentrations of caffeine. One h before i.p. injection ofExpand
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Synergistic induction of sister-chromatid exchanges in lymphocytes from normal subjects and from patients under cytostatic therapy by inhibitors of poly(ADP-ribose)polymerase and antitumour agents.
The effects of nicotinamide on SCE rates induced in vitro by chlorambucil (CBC or melphalan (MELPH) or mitomycin C (MMC) was studied. The combined treatments with either CBC or MELPH or MMC andExpand
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Synergistic induction of cytogenetic damage by alkylating antineoplastics and 5‐azacytidine in human lymphocytes
We studied the effects of the inhibitor of DNA methylation, 5‐azacytidine (Aza‐C), alone and in combination with three antitumor alkylating agents, on sister chromatid exchanges (SCEs) and lymphocyteExpand
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A Comparative Study of the Cytogenetic and Antineoplasmatic Effects Induced by Carboplatin in Combination with Niacin in Human Lymphocytes in vitro and in Ehrlich Ascites Tumor Cells in vivo
Enhanced sister chromatid exchange (SCE) levels and cell division delays were observed when cultured human lymphocytes treated with carboplatin (cPt) were exposed to niacin. Cytogenetic damage wasExpand
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Sister-chromatid exchange, chromosomal aberrations and delays in cell-cycle kinetics in human lymphocytes induced by dental composite resin eluates.
We have investigated eluates derived from commercially available composite resin-based materials used for direct (Tetric Ceram/Ivoclar-Vivadent, Simile/Pentron, Filtek Z-250/3M ESPE) and indirectExpand
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Antileukemic and Cytogenetic Activity by Triple Administration of Three Modified Steroidal Derivatives of Nitrogen Mustards
Combination chemotherapy is widely and routinely used for most cancer patients. The main objective of this study is an effort to develop new anticancer drugs and procedures with enhanced antitumorExpand
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Lack of genotoxicity of silver iodide in the SCE assay in vitro, in vivo, and in the Ames/microsome test.
Silver iodide was evaluated for mutagenicity in the Ames/microsome test (strains TA 1535, TA 102, TA 97, and TA 98) and for the ability to induce Sister Chromatid Exchanges (SCE) in human culturedExpand
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