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Progress and problems in vaccination against necrotic enteritis in broiler chickens
The history of vaccination strategies against necrotic enteritis in broilers is described, the update on future vaccination strategies that are applicable in the field is given and the most important immunogenic and protective proteins that can be used for vaccination are identified. Expand
Protection against avian necrotic enteritis after immunisation with NetB genetic or formaldehyde toxoids☆
Vaccination with a NetB genetic or formaldehyde toxoid protects chicken in an in vivo disease model and could form the bases of an efficient vaccine against necrotic enteritis. Expand
Day-of-hatch vaccination is not protective against necrotic enteritis in broiler chickens
Double vaccination with crude supernatant resulted in a significant decrease in the number of chickens with necrotic enteritis lesions, while vaccination of 1-day-old chickens with crudesupernatant or toxoid, as envisaged for practical field application, did not induce protection. Expand
Variable protection against experimental broiler necrotic enteritis after immunization with the C-terminal fragment of Clostridium perfringens alpha-toxin and a non-toxic NetB variant
The aim of this work was to determine whether immunization with a non-toxic variant of NetB and the C-terminal fragment of C. perfringens alpha-toxin would provide protection against experimental necrotic enteritis. Expand
A colonisation-inhibition culture consisting of Salmonella Enteritidis and Typhimurium ΔhilAssrAfliG strains protects against infection by strains of both serotypes in broilers.
The data suggest that colonisation-inhibition can potentially be used as a versatile control method to protect poultry against several Salmonella serotypes. Expand
Clostridium perfringens alpha toxin and NetB toxin derivatives as vaccine antigens for chickens
De nood aan alternatieven groot en vaccinatie zou de ideale preventiestrategie tegen necrotische enteritis zijn, dus een toegenomen voederconversie. Expand