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Effects of methylmercury on neurotransmitter release from rat brain synaptosomes.
Although the effects of methylmercury (MeHg) at the neuromuscular junction have been well characterized, similar studies employing CNS preparations and transmitters have been limited. We found thatExpand
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Discriminative stimulus properties of pizotifen maleate (BC105): a putative serotonin antagonist
Rats were trained to discriminate the putative serotonin (5-HT) antagonist, pizotifen maleate (BC105), from saline using a two-lever drug discrimination paradigm. Pizotifen maleate (6 mg/kg, 14.6Expand
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Calcium efflux and neurotransmitter release from rat hippocampal synaptosomes exposed to lead.
The results of several studies, employing various tissue preparations, have demonstrated that in vitro Pb exposure has similar effects on the release of several different transmitter substances. PbExpand
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Effect of in vitro inorganic lead on dopamine release from superfused rat striatal synaptosomes.
The effect of inorganic lead in vitro in several aspects of [3H]dopamine release from superfused rat striatal synaptosomes was examined. Under conditions of spontaneous release, lead (1-30 microM)Expand
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The effects of chlordane exposure during pre- and postnatal periods at environmentally relevant levels on sex steroid-mediated behaviors and functions in the rat.
Technical chlordane is a mixture of four main isomers (i.e., heptachlor, cis-chlordane, trans-chlordane, and trans-non-achlor) found in meat and dairy products as well as in indoor air of housesExpand
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Effect of lead exposure on patterns of food intake in weanling rats.
The reduction in growth resulting from lead (PB) exposure in weanling rats is consistent with a lowering of the biological set-point for food intake. In this study the effects of lead on the patternsExpand
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LSD as a discriminative stimulus: role of dorsal raphe nucleus.
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Amphetamine and LSD as discriminative stimuli: Alterations following neonatal monoamine reductions
Male adult Sprague-Dawley rats (70 days of age), neonatally depleted of either 5-hydroxytryptamine (5HT) via 5,7-dihydroxytryptamine (5,7-DHT; ICS) + desmethylimipramine (DMI; IP) at 3 days of age orExpand
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Differential effects of inorganic lead and δ-aminolevulinic acid in vitro on synaptosomal γ-aminobutyric acid release☆☆☆
Several studies have shown that inorganic lead added in vitro does not alter γ-aminobutyric acid (GABA) release from rat brain synaptosomes. The decrease in GABA release observed following chronicExpand
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