• Publications
  • Influence
Design, construction and tests of the ICARUS T600 detector
We have constructed and operated the ICARUS T600 liquid argon (LAr) time projection chamber (TPC). The ICARUS T600 detector is the largest LAr TPC ever built, with a size of about 500 tons of fullyExpand
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Direct measurement of association and dissociation rates of DNA binding in live cells by fluorescence correlation spectroscopy.
Measurement of live-cell binding interactions is vital for understanding the biochemical reactions that drive cellular processes. Here, we develop, characterize, and apply a new procedure to extractExpand
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Adult liver transplantation and abnormalities of splanchnic veins: experience in 53 patients
Abstract The aim of this study was to analyze the influence of technical problems resulting from splanchnic venous anomalies on the outcome of orthotopic liver transplantation. From February 1984Expand
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A New FRAP/FRAPa Method for Three-Dimensional Diffusion Measurements Based on Multiphoton Excitation Microscopy
We present a new convenient method for quantitative three-dimensionally resolved diffusion measurements based on the photobleaching (FRAP) or photoactivation (FRAPa) of a disk-shaped area by theExpand
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Minimizing the impact of photoswitching of fluorescent proteins on FRAP analysis.
Fluorescence recovery after photobleaching (FRAP) is a widely used imaging technique for measuring the mobility of fluorescently tagged proteins in living cells. Although FRAP presumes thatExpand
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Two-Photon Excitation Fluorescence Microscopy
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First results from the HDMS experiment in the final setup
Abstract The Heidelberg dark matter search (HDMS) is an experiment designed for the search for weakly interacting massive particle dark matter. It is using a special configuration of Ge detectors, toExpand
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Role of three-dimensional bleach distribution in confocal and two-photon fluorescence recovery after photobleaching experiments.
The quantitative analysis of fluorescence perturbation experiments such as fluorescence recovery after photobleaching (FRAP) requires suitable analytical models to be developed. When diffusion in 3DExpand
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Surgical treatment of a double splenic artery aneurysm.
Splenic artery aneurysms account for the majority of splanchnic artery aneurysms. These constitute a uncommon pathology, but with a mortality rate greater 70%. We report a case of a doubleExpand
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Cyclopamine-Paclitaxel-Containing Nanoparticles: Internalization in Cells Detected by Confocal and Super-Resolution Microscopy.
Cyclopamine- and paclitaxel-containing hetero-nanoparticles generated by self-assembly show combined efficacy in the treatment of three different cancer cell lines. The use of ternary combinationExpand
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