• Publications
  • Influence
Spatial organization of chromosomes in the salivary gland nuclei of Drosophila melanogaster
Using a computer-based system for model building and analysis, three- dimensional models of 24 Drosophila melanogaster salivary gland nuclei have been constructed from optically or physicallyExpand
  • 195
  • 10
Characteristic folding pattern of polytene chromosomes in Drosophila salivary gland nuclei
A computer-based system for recording and analysing light microscope images, combined with classical cytogenetic analysis, has revealed the spatial organization of the giant chromosomes of DrosophilaExpand
  • 98
  • 1
Spatial Organization of the Drosophila Nucleus: A Three-Dimensional Cytogenetic Study
SUMMARY The combination of optical fluorescence microscopy with digital image processing and analysis has been used to examine the three-dimensional organization of chromosomes within intact polyteneExpand
  • 30
  • 1
The three-dimensional organization of polytene nuclei in male Drosophila melanogaster with compound XY or ring X chromosomes.
The three-dimensional organization of polytene chromosomes within nuclei containing rearranged X chromosomes was examined in male Drosophila melanogaster. Salivary glands of third instar larvaeExpand
  • 19
  • 1
Light microscope based analysis of three-dimensional structure: applications to the study of Drosophila salivary gland nuclei. I. Data collection and analysis.
Many biological structures of interest are large enough that they may be viewed by light microscope methods, yet they are sufficiently complicated that interpretation of what is seen is quiteExpand
  • 8
Light microscope based analysis of three-dimensional structure: applications to the study of Drosophila salivary gland nuclei. II. Algorithms for model analysis.
  • D. Mathog
  • Medicine, Biology
  • Journal of microscopy
  • 1 March 1985
In Drosophila melanogaster there are significant differences in the way the polytene chromosomes are arranged in different nuclei from the same salivary gland (Mathog et al., 1984). Visual inspectionExpand
  • 7