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The effects of alcohol on the cognitive function of males and females and on skills relating to car driving
Nine male and nine female subjects received one of four doses of alcohol (0‐25, 0‐5, 0‐75 or 1 g per kg of bodyweight for male subjects: females received 92% of these values) or placebo. Similar… Expand
Behavioral and physiological indices of fatigue in a visual tracking task
It was concluded that it may be possible to detect the onset of fatigue before any significant deterioration in operator performance occurs. Expand
A randomised, controlled trial of fluoxetine in methadone maintenance patients with depressive symptoms.
- A. Dean, J. Bell, D. Mascord, G. Parker, M. Christie
- Psychology, Medicine
- Journal of affective disorders
- 1 October 2002
Little evidence supports use of fluoxetine as a treatment for depressive symptoms in MMPs, and significant improvements were observed in depression, life functioning, and social impairment. Expand
Effect of diet on [lactate]/[pyruvate] ratios during alcohol metabolism in man.
Blood [lactate]/[pyruvate] ratios were significantly higher during fasting alcohol metabolism after the low-carbohydrate, high-fat diet, which may affect cytoplasmic-mitochondrial NADH transfer. Expand
EFFECTS OF PSYCHOACTIVE DRUGS ON CAR DRIVING PERFORMANCE: DRUGS IN CRASH‐INVOLVED DRIVERS
DRUG USAGE BY PERSONS SUSPECTED OF DRIVING UNDER THE INFLUENCE OF A DRUG
The procedures adopted in the taking of blood samples, the incidence of various drugs in apprehended and accident-involved drivers, a description of the population of suspected drug-impaired drivers and the reason for coming to police notice are presented. Expand
COMPARISON OF FIVE COMMONLY ABUSED STIMULANTS WHICH ARE USED TO REDUCE FATIGUE
The results suggest that none of the five stimulants, when taken in normal therapeutic doses, differ greatly in their capacity to improve performance and that differences among the drugs are mainly related to their effects on the cardiovascular system. Expand
Effect of oral glucose on the rate of metabolism of ethanol in humans.
The presence or absence of a change in the rate of alcohol metabolism after glucose was associated with the subject's fasting rate and with their glucose tolerance, and there were differences between the subjects. Expand
The effect of fructose on alcohol metabolism and on the [lactate]/[pyruvate] ratio in man.
Since fructose increased the [lactate]/[pyruvate] ratio when it increased alcohol metabolism, the action of fructose cannot be explained by a decrease in the liver cytoplasmic [NADH/[NAD] ratio and some other mechanism must be sought. Expand
Studies on the chronopharmacology of ethanol.
It appears that major circadian variability in the metabolic and/or behavioural effects of ethanol is unlikely to occur, and the only significant diurnal variations in the response to ethanol were for plasma cortisol concentrations and body temperature. Expand