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A reasonably sensitive and specific noninvasive test for doxorubicin cardiotoxicity is needed. In addition, few data exist on the short- and long-term effects of doxorubicin on diastolic filling. To… (More)
BACKGROUND Hydroxyurea is an S-phase specific drug. Constant exposure of tumor cells with a low S-phase fraction to the agent may result in improved cell kill. Because of its short half-life, a… (More)
The effect if any of prepared frozen grapefruit juice on prothrombin times (PTs) in patients undergoing stabilized warfarin therapy was studied. Patients receiving low-intensity warfarin therapy… (More)
Using the theory of geodesics on surfaces of revolution, we show that any two-dimensional orbifold of revolution homeomorphic to S2 must contain an infinite number of geometrically distinct closed… (More)
Using the theory of geodesics on surfaces of revolution, we introduce the period function. We use this as our main tool in showing that any two-dimensional orbifold of revolution homeomorphic to S^2… (More)
Ab initio based Car-Parrinello molecular dynamics calculations (CPMD) have been used to investigate the properties of crystalline nitric acid trihydrate (NAT) at 195 K. The crystal unit cell consists… (More)