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Malaria DNA vaccines in Aotus monkeys.
It is demonstrated in Aotus monkeys that an intradermal route of immunization with a PyCSP plasmid DNA vaccine generates antibody responses equivalent to a multiple antigen peptide/adjuvant based vaccine, and that these data support the use of the intrader mal route for initial studies of the efficacy of DNA vaccines. Expand
Optimization of antibody responses of a malaria DNA vaccine in Aotus monkeys
Humoral immune responses against Plasmodium vivax MSP1 in humans living in a malaria endemic area in Flores, Indonesia.
- M. Ak, T. Jones, +6 authors S. Hoffman
- Biology, Medicine
- The Southeast Asian journal of tropical medicine…
- 1 December 1998
The frequency of antibody positivity to MSP1 antigen in ELISA increased with age reaching a maximum of 89% in > or = 20 years old, and with a decline in the prevalence of parasitemia. Expand