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Consensus recommendations for the use of 18F-FDG PET as an indicator of therapeutic response in patients in National Cancer Institute Trials.
- L. Shankar, J. Hoffman, +9 authors D. Sullivan
- Journal of nuclear medicine : official…
- 1 June 2006
1Cancer Imaging Program, National Cancer Institute, National Institutes of Health, Bethesda, Maryland; 2Division of Nuclear Medicine, Huntsman Cancer Institute, University of Utah School of Medicine,… Expand
Imaging P‐glycoprotein Transport Activity at the Human Blood‐brain Barrier with Positron Emission Tomography
- L. Sasongko, J. Link, +5 authors J. Unadkat
- Chemistry, Medicine
- Clinical pharmacology and therapeutics
- 1 June 2005
Numerous knockout mouse studies have revealed that P‐glycoprotein (P‐gp) significantly limits drug distribution across the mouse blood‐brain barrier (BBB). To determine the importance of P‐gp at the… Expand
Progress and Promise of FDG-PET Imaging for Cancer Patient Management and Oncologic Drug Development
2-[18F]Fluoro-2-deoxyglucose positron emission tomography (FDG-PET) assesses a fundamental property of neoplasia, the Warburg effect. This molecular imaging technique offers a complementary approach… Expand
Phase II Study of Daily Sunitinib in FDG-PET–Positive, Iodine-Refractory Differentiated Thyroid Cancer and Metastatic Medullary Carcinoma of the Thyroid with Functional Imaging Correlation
Purpose: We conducted a phase II study to assess the efficacy of continuous dosing of sunitinib in patients with flurodeoxyglucose positron emission tomography (FDG-PET)–avid, iodine-refractory… Expand
Positron emission tomography imaging of brain tumors.
Energy metabolism and amino acid transport and incorporation are important components of the pathophysiology of gliomas, about which molecular imaging is providing regional biologic information that… Expand
Application of Photoshop-based Image Analysis to Quantification of Hormone Receptor Expression in Breast Cancer
- H. A. Lehr, D. Mankoff, D. Corwin, G. Santeusanio, A. Gown
- Medicine, Biology
- The journal of histochemistry and cytochemistry…
- 1 November 1997
The benefit of quantifying estrogen receptor (ER) and progesterone receptor (PR) expression in breast cancer is well established. However, in routine breast cancer diagnosis, receptor expression is… Expand
Hypoxia and Glucose Metabolism in Malignant Tumors
Purpose: The aim of this study is to compare glucose metabolism and hypoxia in four different tumor types using positron emission tomography (PET). 18F-labeled fluorodeoxyglucose (FDG) evaluates… Expand
18fluorodeoxyglucose positron emission tomography to detect mediastinal or internal mammary metastases in breast cancer.
- W. B. Eubank, D. Mankoff, +10 authors R. Livingston
- Journal of clinical oncology : official journal…
- 1 August 2001
PURPOSE To determine the prevalence of suspected disease in the mediastinum and internal mammary (IM) node chain by 18fluorodeoxyglucose (FDG) positron emission tomography (PET), compared with… Expand
Increased false negative sentinel node biopsy rates after preoperative chemotherapy for invasive breast carcinoma.
BACKGROUND Sentinel lymph node dissection (SLND) has been a promising new technique in breast carcinoma staging, but could be unreliable in certain patient subsets. The current study assessed whether… Expand
Monitoring the response of patients with locally advanced breast carcinoma to neoadjuvant chemotherapy using [technetium 99m]‐sestamibi scintimammography
- D. Mankoff, L. K. Dunnwald, J. Gralow, G. K. Ellis, M. J. Drucker, R. Livingston
- 1 June 1999
Mammographic and physical examination assessments of the response of locally advanced breast carcinoma (LABC) to neoadjuvant therapy have been shown to be inaccurate. The authors studied the… Expand