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A new class of inhibitors of cAMP-mediated Cl− secretion in rabbit colon, acting by the reduction of cAMP-activated K+ conductance
Previously we have shown that arylamino-benzoates like 5-nitro-2-(3-phenylpropylamino)-benzoate (NPPB), which are very potent inhibitors of NaCl absorption in the thick ascending limb of the loop ofExpand
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Selective inhibitors of KCl cotransport in human red cells
Two analogues of the loop diuretics furosemide and bumetanide have been identified as differential inhibitors of KCl and NaKCl cotransport systems, assayed by measuring K+ influx in ‘young’ human redExpand
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Cardiovascular effects of the novel potassium channel opener (3S,4R)-3-hydroxy-2,2-dimethyl-4-(2-oxo- 1-pyrrolidinyl)-6-phenylsulfonylchromane hemihydrate.
Cardiovascular effects of the novel potassium channel opener (3S,4R)-3-hydroxy-2,2-dimethyl-4-(2-oxo-1-pyrrolidinyl)-6- phenylsulfonylchromane hemihydrate (Hoe 234, CAS 132014-21-2) were investigatedExpand
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Cardioselective K(ATP) channel blockers derived from a new series of m-anisamidoethylbenzenesulfonylthioureas.
Sulfonylthioureas exhibiting cardioselective blockade of ATP-sensitive potassium channels (K(ATP) channels) were discovered by stepwise structural variations of the antidiabetic sulfonylureaExpand
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Epi-6-aminopenicillanic acid and epipenicillin G.
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The structure of telomycin.
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Benzenesulfonyl-ureas and -thioureas substituted, process for their preparation and their use in the production of pharmaceutical preparations, as well as pharmaceutical preparations containing them.
BENZOLSULFONILUREAS and -thioureas substituted formula I, wherein R (1) is hydrogen, alkyl having 1, 2, 3, 4, 5 or 6 carbon atoms CO cycloalkyl having 3, 4, 5 or 6 carbon atoms; R (2) is alkyl havingExpand
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