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The mTOR signaling pathway regulates pain-related synaptic plasticity in rat entorhinal-hippocampal pathways
BackgroundOur previous work demonstrated that persistent peripheral nociception (PPN) leads to synaptic plasticity and functional changes in the rat hippocampus. The protein kinase mTOR is a critical… Expand
Association between the ERCC1 polymorphism and platinum-based chemotherapy effectiveness in ovarian cancer: a meta-analysis
BackgroundOvarian cancer is a prominent public health problem which affects people all around the world. Platinum-based chemotherapy is a common treatment for ovarian cancer, however, the… Expand
Neonatal ketamine exposure-induced hippocampal neuroapoptosis in the developing brain impairs adult spatial learning ability
Ketamine exposure can lead to selective neuroapoptosis in the developing brain. p66ShcA, the cellular adapter protein expressed selectively in immature neurons, is a known pro-apoptotic molecule that… Expand
[Preparation and characterization of mouse polyclonal antibody against conserved region of human FOXO3].
Objective To purify the recombinant protein specific to conserved region of forkhead box O3 (FOXO3) and prepare mouse anti-human FOXO3 polyclonal antibody. Methods The DNA fragment (aa290-472)… Expand
Different Effects of p52SHC1 and p52SHC3 on the Cell Cycle of Neurons and Neural Stem Cells
SHC3 is exclusively expressed in postmitotic neurons, while SHC1 is found in neural stem cells and neural precursor cells but absent in mature neurons. In this study, we discovered that suppression… Expand
TGR5 agonist INT-777 mitigates inflammatory response in human endometriotic stromal cells: A therapeutic implication for endometriosis.
- D. Lyu, N. Tang, +4 authors Huizhen Liu
- Chemistry, Medicine
- International immunopharmacology
- 14 March 2019
Endometriosis is a condition characterized by the presence of endometrial tissues outside the uterus. Endometriotic stromal cells (ESCs) are known to undergo regeneration and are linked to the… Expand
Research and application of information service platform for agricultural economic cooperation organization based on Hadoop cloud computing platform environment: taking agricultural and fresh…
This paper mainly introduces the cloud service platform based on Hadoop, and analyzes the application of cloud services in agricultural informatization. Expand
[Alveolar soft part sarcoma of the head and neck: clinical and imaging features in two cases].
A Comparison of Vocational Education in China and Japan
After more than 30 years of reform and development, vocational education in Japan has become more and more adapted to the market requirements, and graduates from vocational education schools are… Expand
[Clinical analysis of one case of giant petrous apex cholesteatoma].