• Publications
  • Influence
Highly Efficient Neural Conversion of Human Pluripotent Stem Cells in Adherent and Animal‐Free Conditions
Neural differentiation of human embryonic stem cells (hESCs) and induced pluripotent stem cells (hiPSCs) can produce a valuable and robust source of human neural cell subtypes, holding great promiseExpand
  • 22
  • 3
  • PDF
Synthetic pulmonary surfactant preparations: new developments and future trends.
Pulmonary surfactant is a lipid-protein complex that coats the interior of the alveoli and enables the lungs to function properly. Upon its synthesis, lung surfactant adsorbs at the interface betweenExpand
  • 59
  • 2
  • PDF
Human iPSC derived disease model of MERTK-associated retinitis pigmentosa
Retinitis pigmentosa (RP) represents a genetically heterogeneous group of retinal dystrophies affecting mainly the rod photoreceptors and in some instances also the retinal pigment epithelium (RPE)Expand
  • 36
  • 2
  • PDF
Complete rat spinal cord transection as a faithful model of spinal cord injury for translational cell transplantation
Spinal cord injury (SCI) results in neural loss and consequently motor and sensory impairment below the injury. There are currently no effective therapies for the treatment of traumatic SCI inExpand
  • 39
  • 2
Interfacial behavior of recombinant forms of human pulmonary surfactant protein SP-C.
The behavior at air-liquid interfaces of two recombinant versions of human surfactant protein SP-C has been characterized in comparison with that of native palmitoylated SP-C purified from porcineExpand
  • 13
  • 2
Influence of hydrophobic matching on association of model transmembrane fragments containing a minimised glycophorin A dimerisation motif
The principles that govern the folding and packing of membrane proteins are still not completely understood. In the present work, we have revisited the glycophorin A (GpA) dimerisation motif thatExpand
  • 28
  • 1
Hypoxia Increases the Yield of Photoreceptors Differentiating from Mouse Embryonic Stem Cells and Improves the Modeling of Retinogenesis In Vitro
Retinitis pigmentosa (RP), a genetically heterogeneous group of diseases together with age‐related macular degeneration (AMD), are the leading causes of permanent blindness and are characterized byExpand
  • 31
  • 1
Concentration dependent effects of commonly used pesticides on activation versus inhibition of the quince (Cydonia Oblonga) polyphenol oxidase.
Polyphenol oxidase (PPO) catalyzes the oxidation of o-diphenols to their respective quinones which undergo autopolymerization and form dark pigments. The interaction of PPO with various substratesExpand
  • 10
  • 1
Production and characterisation of recombinant forms of human pulmonary surfactant protein C (SP-C): Structure and surface activity.
Surfactant protein C (SP-C) is an essential component for the surface tension-lowering activity of the pulmonary surfactant system. It contains a valine-rich alpha helix that spans the lipid bilayer,Expand
  • 21
Concise Review: Human Induced Pluripotent Stem Cell Models of Retinitis Pigmentosa
Hereditary retinal dystrophies, specifically retinitis pigmentosa (RP) are clinically and genetically heterogeneous diseases affecting primarily retinal cells and retinal pigment epithelial cellsExpand
  • 14
  • PDF