• Publications
  • Influence
Antioxidant enzymes in the digestive gland of the common musselMytilus edulis
Antioxidant enzymes function to remove deleterious reactive oxygen species, including the superoxide anion radical and H2O2. Subcellular distributions and optimal and other properties of catalaseExpand
Oxyradical production as a pollution-mediated mechanism of toxicity in the common mussel, Mytilus edulis L., and other molluscs
Normal and pollution-enhanced oxy- radical (02-, H202, OH)* production in molluscs have been reviewed and discussed. Additionally, data are presented on the antioxidant enzyme responses and lipidExpand
Oxidative Stress in Aquatic Organisms in Relation to Pollution and Aquaculture
SUMMARY Recent studies indicate that contaminant-stimulated reactive oxygen species (ROS) production, and resulting oxidative damage, may be a significant mechanism of toxicity in aquatic organismsExpand
The fate of organic xenobiotics in aquatic ecosystems: quantitative and qualitative differences in biotransformation by invertebrates and fish.
  • D. Livingstone
  • Biology, Medicine
  • Comparative biochemistry and physiology. Part A…
  • 1 May 1998
Use of the same approach showed that fish metabolise pentachlorophenol (PCP) and benzo[a]pyrene (BaP) faster than certain aquatic invertebrates, viz. molluscan species and crustacean species, and the higher rate of biotransformation of BaP in fish is consistent with higher levels of total cytochrome P450 and inducible cy tochrome P4501A (CYP1A) activity. Expand
Physiological and biochemical responses of bivalve molluscs to exposure to air
All species show an apparent oxygen debt after exposure to air, the extent of which is not simply related to either the level of aerobic respiration or the degree of anaerobiosis during exposure, and the relative energy yields by aerobic and anaerobic means are discussed. Expand
Organic Xenobiotic Metabolism in Marine Invertebrates
Central to the defense against such an enormous and diverse number of potentially toxic compounds is an impressive array of enzymes, which function ideally to detoxify and eliminate xenobiotics from an organism. Expand
Seasonal variations in the antioxidant defence systems and lipid peroxidation of the digestive gland of mussels.
The obtained data indicate that a reduction of the antioxidant defence systems, occurring during winter, could be directly responsible for an enhanced susceptibility of mussels tissues to oxidative stress, as indicated by the high MDA concentration observed in this period. Expand
Responses of hepatic biotransformation and antioxidant enzymes to CYP1A-inducers (3-methylcholanthrene, β-naphthoflavone) in sea bass (Dicentrarchus labrax), dab (Limanda limanda) and rainbow trout
Abstract The time-course responses of hepatic biotransformation and antioxidant enzymes to cytochrome P4501A-inducers in fish were examined using marine and freshwater species, viz. respectively, seaExpand
Age-related changes in antioxidant enzyme activities, fatty acid composition and lipid peroxidation in whole body Gammarus locusta (Crustacea: Amphipoda)
Overall, the decline in antioxidant enzyme activities, coupled with increased levels of PUFA, as the individual grows older, may render the older animals more susceptible to lipid peroxidation and oxidative stress. Expand