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Alterations of growth factor transcripts in rat lungs during development of monocrotaline-induced pulmonary hypertension.
Although pathologic and hemodynamic changes in monocrotaline (MCT)-induced pulmonary hypertension have been studied extensively, relatively little is known about the inter- and intracellular… Expand
A novel technique for visualizing the intracellular localization and distribution of transported polyamines in cultured pulmonary artery smooth muscle cells.
- S. Aziz, M. Yatin, D. Worthen, D. Lipke, P. Crooks
- Chemistry, Medicine
- Journal of pharmaceutical and biomedical analysis
- 1 June 1998
The use of a combination of monofluorescein adducts of spermidine (FL-SPD) and spermine (FL-SPM) with confocal laser scanning microscopy (CLSM) provides a useful means for monitoring the fate and… Expand
Blood volume and red cell space in tissues of the rainbow trout, Salmo gairdneri.
- D. Duff, D. Fitzgerald, D. Kullman, D. Lipke, J. Ward, K. Olson
- Biology, Medicine
- Comparative biochemistry and physiology. A…
1. Whole body blood volume and red cell space of 22 tissues were measured in unanesthetized rainbow trout at 4, 12, 30, 60, 150 and 240 min after dorsal aortic injection of 51Cr-labeled red blood… Expand
Temporal alterations in basement membrane components in the pulmonary vasculature of the chronically hypoxic rat: impact of hypoxia and recovery.
- A. C. Vyas-Somani, S. Aziz, S. Arcot, M. Gillespie, J. Olson, D. Lipke
- The American journal of the medical sciences
- 1 August 1996
The hypoxic model of pulmonary hypertension was used to examine temporal alterations in the deposition of the basement membrane (BM) and components of fibronectin, laminin, and Type IV collagen… Expand
Enzymes of the kallikrein-kinin system in rainbow trout.
Evidence for a kallikrein-kinin system (KKS) in fish is incomplete. In the present study, components of the KKS were identified in rainbow trout. Tissues were assayed for kallikrein-like esterolytic… Expand
Temporal alterations in specific basement membrane components in lungs from monocrotaline-treated rats.
- D. Lipke, S. Arcot, M. Gillespie, J. Olson
- Biology, Medicine
- American journal of respiratory cell and…
- 1 October 1993
The present study utilized the monocrotaline (MCT) model of pulmonary hypertension in rats to examine temporal alterations in steady-state levels of basement membrane (BM) component mRNA and… Expand
Near net-shape/net-dimension ZrC/W-based composites with complex geometries via rapid prototyping and Displacive Compensation of Porosity
Abstract ZrC/W-based composites with complex shapes have been fabricated by combining rapid prototyping methods for synthesizing porous WC preforms with the shape/dimension-preserving, reactive… Expand
A specific inhibitor of mammalian kallikrein, Phe-Phe-Arg-chloromethyl ketone, inhibits the production of vasoactive substances from trout plasma by kallikrein and blocks endogenous kallikrein-like…
The cardiovascular effects of the kallikrein-kinin system (KKS) have not been completely characterized in lower vertebrates. In the present study, a specific, irreversible kallikrein inhibitor,… Expand
Intragranular Tungsten/Zirconium Carbide Nanocomposites via a Selective Liquid/Solid Displacement Reaction
A selective liquid/solid displacement reaction has been used, for the first time, to convert non-oxide ceramic solid solutions into composites comprised of intragranular metal nanoparticles embedded… Expand