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Studies on the composition and structure of plasma lipoproteins. Distribution of lipoprotein families in major density classes of normal human plasma lipoproteins.
Abstract To account for the protein heterogeneity of lipoprotein preparations isolated by ultracentrifugal or precipitation techniques, we have proposed a classification system [P. Alaupovic et al.,… Expand
Properties of apolipoprotein B in urea and in aqueous buffers. The use of glutathione and nitrogen in its solubilization.
Abstract Based on the assumption that lipid peroxidation of low density lipoproteins (LDL) may be the main cause of the insolubility of the major protein moiety, apolipoprotein B, we have developed a… Expand
Malondialdehyde formation in stored plasma.
- D. Lee
- Chemistry, Medicine
- Biochemical and biophysical research…
- 29 August 1980
Summary The formation of malondialdehyde in plasma during storage was used as an indicator of lipid peroxidation. Malondialdehyde concentrations were measured in plasma stored at 4°C in the presence… Expand
Glucose tolerance and plasma lipid distributions in rats fed a high-sucrose, high-cholesterol, low-chromium diet.
- D. Donaldson, D. Lee, C. C. Smith, O. Rennert
- Biology, Medicine
- Metabolism: clinical and experimental
- 1 December 1985
Male Sprague-Dawley rats were fed either a low-chromium (60 to 100 micrograms per kg of diet) or chromium-supplemented (5 mg per kg of diet), high-sucrose, high-cholesterol diet from weaning until… Expand
Oxidative Stress and Inflammation in Renal Patients and Healthy Subjects
The first goal of this study was to measure the oxidative stress (OS) and relate it to lipoprotein variables in 35 renal patients before dialysis (CKD), 37 on hemodialysis (HD) and 63 healthy… Expand
Studies of the composition and structure of plasma lipoproteins. Isolation, composition, and immunochemical characterization of low density lipoprotein subfractions of human plasma.
Composition and concentration of apolipoproteins in very-low-and low-density lipoproteins of normal human plasma.
A novel method for converting apolipoprotein B, the major protein moiety of human plasma low density lipoproteins, into a water-soluble protein.
We have developed a new technique to solubilize apolipoprotein B (ApoB) in aqueous solutions. The procedure involves stirring ApoB in 6 M guanidine/20 mM NH4Cl/NH4OH in the presence of cupric ammonia… Expand
Evaluation of immunoaffinity chromatography for isolating human lipoproteins containing apolipoprotein B.
Because of high specificity, immunoaffinity chromatography is the most suitable procedure for the isolation of lipoprotein (LP) particles defined by their apolipoprotein (Apo) composition. The… Expand
Lipid peroxidation and antioxidant vitamins prior to, during, and after correction of diabetic ketoacidosis.
- D. Lee, W. Hoffman, G. Carl, M. Khichi, P. Cornwell
- Journal of diabetes and its complications
- 1 July 2002
Oxidative stress plays an important role in the chronic complications of insulin-dependent diabetes mellitus (IDDM). Hyperketonemia, as well as hyperglycemia, is involved in the generation of… Expand