• Publications
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Inference of Population Structure using Dense Haplotype Data
The advent of genome-wide dense variation data provides an opportunity to investigate ancestry in unprecedented detail, but presents new statistical challenges. We propose a novel inference frameworkExpand
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The fine-scale genetic structure of the British population
Fine-scale genetic variation between human populations is interesting as a signature of historical demographic events and because of its potential for confounding disease studies. We useExpand
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Likelihood-free estimation of model evidence
tl;dr
We present a method for estimating the evidence of a model when the likelihood p(xobs|M) is not available in the sense that it either cannot be evaluated or such evaluation is prohibitively expensive. Expand
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Genomic analyses inform on migration events during the peopling of Eurasia
High-coverage whole-genome sequence studies have so far focused on a limited number of geographically restricted populations, or been targeted at specific diseases, such as cancer. Nevertheless, theExpand
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Genome-Wide Analysis of Cold Adaptation in Indigenous Siberian Populations
Following the dispersal out of Africa, where hominins evolved in warm environments for millions of years, our species has colonised different climate zones of the world, including high latitudes andExpand
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A tutorial on how not to over-interpret STRUCTURE and ADMIXTURE bar plots
Genetic clustering algorithms, implemented in programs such as STRUCTURE and ADMIXTURE, have been used extensively in the characterisation of individuals and populations based on genetic data. AExpand
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RADpainter and fineRADstructure: Population Inference from RADseq Data
Abstract Powerful approaches to inferring recent or current population structure based on nearest neighbor haplotype “coancestry” have so far been inaccessible to users without high qualityExpand
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Genetic architecture: the shape of the genetic contribution to human traits and disease
Genetic architecture describes the characteristics of genetic variation that are responsible for heritable phenotypic variability. It depends on the number of genetic variants affecting a trait,Expand
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Population identification using genetic data.
  • D. Lawson, D. Falush
  • Biology, Medicine
  • Annual review of genomics and human genetics
  • 12 September 2012
A large number of algorithms have been developed to classify individuals into discrete populations using genetic data. Recent results show that the information used by both model-based clusteringExpand
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A tutorial on how (not) to over-interpret STRUCTURE/ADMIXTURE bar plots
Genetic clustering algorithms, implemented in popular programs such as STRUCTURE and ADMIXTURE, have been used extensively in the characterisation of individuals and populations based on geneticExpand
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