• Publications
  • Influence
Macrophage and retinal pigment epithelium expression of angiogenic cytokines in choroidal neovascularization.
TLDR
This study shows that RPE cells express MCP, a cytokine involved with macrophage recruitment, and that macrophages express TF in CNV, thus perpetuating angiogenesis. Expand
The neuregulin, glial growth factor 2, diminishes autoimmune demyelination and enhances remyelination in a chronic relapsing model for multiple sclerosis.
TLDR
A beneficial effect of a neurotrophic growth factor has been demonstrated on the clinical, pathologic, and molecular manifestations of autoimmune demyelination, an effect that was associated with increased expression of a T helper 2 cytokine. Expand
Angiogenic and lymphangiogenic microvessel density in breast carcinoma: correlation with clinicopathologic parameters and VEGF-family gene expression
TLDR
Measurements of angiogenesis and lymphangiogenesis may have utility for breast cancer pathology, particularly for estimation of metastatic risk, and could suggest a selective role of VEGF-C and V EGF-D in lymphangaogenesis. Expand
TTF‐1 and Napsin A double stain
TLDR
A combined double stain for TTF‐1 and napsin A has been proposed to achieve higher sensitivity and specificity in the diagnosis of lung adenocarcinoma in cell blocks of fine‐needle aspirates (FNA). Expand
Survivin Expression in Ovarian Carcinoma: Correlation with Apoptotic Markers and Prognosis
TLDR
The majority (74%) of ovarian carcinoma show survivin expression, which correlates with poor prognostic parameters (high grade, histologic type, p53 mutation) but not with survival, and Therapeutic targeting of survivin in ovarian carcinomas is a future possibility. Expand
Claudin-7 immunohistochemistry in renal tumors: a candidate marker for chromophobe renal cell carcinoma identified by gene expression profiling.
TLDR
Based on microarray and immunohistochemical data, claudin-7 is proposed to be a candidate expression marker for distinguishing chromophobe RCC from other renal tumor subtypes, including the morphologically similar oncocytoma. Expand
Combined double CK5/P63 stain: Useful adjunct test for diagnosing pulmonary squamous cell carcinoma
TLDR
This first study of double staining of CK5/P63 in FNA CB shows a sensitivity of 70% and specificity of 100% for SQCC of the lung, and can help in the diagnosis of pulmonary SQCC with an accuracy of 88% and a positive predictive value of 100%. Expand
SOX10 Expression in Malignant Melanoma, Carcinoma, and Normal Tissues
TLDR
SOX10 is a sensitive, specific marker for melanoma, but as benign nevi also express SOX10, it cannot be used to differentiate between benign and malignant pigmented skin lesions. Expand
The roles of calcium signaling and ERK1/2 phosphorylation in a Pax6+/- mouse model of epithelial wound-healing delay
TLDR
The study links Pax6 deficiency to a previously overlooked wound-healing delay and demonstrates that defective calcium signaling in Pax6+/- cells underlies this delay, and shows that it can be pharmacologically corrected. Expand
Survivin and Caspase-3 Expression in Breast Cancer: Correlation With Prognostic Parameters, Proliferation, Angiogenesis, and Outcome
TLDR
Survivin and caspase-3 expression correlate with poor prognostic parameters (higher histologic grade and high proliferation), but not with outcome, in breast carcinoma patients. Expand
...
1
2
3
4
5
...