D. Laaksonen

Publications171
h-index59
Citations18,988
Highly Influential Citations696
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The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men.
TLDR
Cardiovascular disease and all-cause mortality are increased in men with the metabolic syndrome, even in the absence of baseline CVD and diabetes, according to the Kuopio Ischaemic Heart Disease Risk Factor Study.
Metabolic syndrome and development of diabetes mellitus: application and validation of recently suggested definitions of the metabolic syndrome in a prospective cohort study.
TLDR
The authors assessed the sensitivity and specificity of the definitions of the metabolic syndrome for prevalent and incident diabetes mellitus in a Finnish population-based cohort of middle-aged men followed for 4 years since the late 1980s.
Low levels of leisure-time physical activity and cardiorespiratory fitness predict development of the metabolic syndrome.
TLDR
High-risk men engaging in currently recommended levels of physical activity were less likely to develop the metabolic syndrome than sedentary men and cardiorespiratory fitness was also strongly protective, although possibly not independent of mediating factors.
Back and hip extensor fatigability in chronic low back pain patients and controls.
TLDR
The EMG fatigue analysis results suggest that the gluteus maximus muscles are more fatigable in chronic low back pain patients than in healthy control subjects during a sustained back extension endurance test.
Testosterone and sex hormone-binding globulin predict the metabolic syndrome and diabetes in middle-aged men.
TLDR
Low total testosterone and SHBG levels independently predict development of the metabolic syndrome and diabetes in middle-aged men, and hypoandrogenism is an early marker for disturbances in insulin and glucose metabolism that may progress to the metabolic Syndrome or frank diabetes and may contribute to their pathogenesis.
Physical activity in prevention and treatment of the metabolic syndrome.
TLDR
W brisk walking for at least 30 min daily can be recommended as the principal form of physical activity at the population level and, if there are no contraindications, more vigorous physical exercise or resistance training should also be considered to obtain additional health benefits.
Exercise training modulates heat shock protein response in diabetic rats.
TLDR
Examination of the effect of 8 wk of endurance training on HSP expression and oxidative stress markers in the skeletal muscle, heart, and liver of streptozotocin-induced diabetic and nondiabetic control rats suggests that diabetes impairs HSP protection.
Dietary fatty acids and cardiovascular disease: an epidemiological approach.
TLDR
Findings from metabolic and clinical studies reinforce findings from observational studies supporting recommendations to replace saturated and trans fat with unsaturated fat in the prevention of cardiovascular disease.
Sedentary lifestyle, poor cardiorespiratory fitness, and the metabolic syndrome.
TLDR
Measurement of VO(2max) in sedentary men with risk factors may provide an efficient means for targeting individuals who would benefit from interventions to prevent the MS and its consequences.
Age, sex, and body mass index as determinants of back and hip extensor fatigue in the isometric Sørensen back endurance test.
TLDR
The validity of this widely used isometric back endurance test in specifically measuring lumbar paraspinal muscle endurance is questionable, as is the direct comparison of test results between women and men.
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