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Effects of Vitamin D Supplementation on Cognitive and Emotional Functioning in Young Adults – A Randomised Controlled Trial
TLDR
It is indicated that vitamin D supplementation does not influence cognitive or emotional functioning in healthy young adults and future controlled trials in targeted populations of interest are required to determine whether supplementation can improve functioning in these domains. Expand
Transcriptome and venom proteome of the box jellyfish Chironex fleckeri
TLDR
This study provides the first overview of a box Jellyfish transcriptome which, coupled with venom proteomics data, enhances the current understanding of box jellyfish venom composition and the molecular structure and function of cnidarian toxins. Expand
Extravillous trophoblast cells-derived exosomes promote vascular smooth muscle cell migration
TLDR
The data obtained in this study are consistent with the hypothesis that the release, content, and bioactivity of exosomes derived from EVT-like cell lines is cell origin-dependent and differentially regulates VSMC migration. Expand
Measurements of 25-hydroxyvitamin D concentrations in archived dried blood spots are reliable and accurately reflect those in plasma.
TLDR
A simple calibration model was developed to convert measurements from DBS to equivalent plasma measurements, thus enabling comparisons against clinical reference ranges and with studies using sera or plasma samples. Expand
Profiling of Free Fatty Acids Using Stable Isotope Tagging Uncovers a Role for Saturated Fatty Acids in Neuroexocytosis.
TLDR
An "iTRAQ"-like method for profiling FFAs by stable isotope tagging (FFAST), based on the differential labeling of the carboxyl group and designed to resolve analytical variance, through a multiplexed assay in cells and subcellular fractions is developed. Expand
Distribution of 25-hydroxyvitamin D3 in dried blood spots and implications for its quantitation by tandem mass spectrometry.
TLDR
Investigation of potential factors that may affect the analysis of 25OHD(3) in prospective cohorts of DBS, such as blood spot volume, hole punch position, and paper type, revealed a chromatographic effect across the surface of blood spots that may potentially explain why the diffusion properties of blood and type of Chromatographic paper may significantly influence the distribution of such analytes in DBS. Expand
The association between neonatal vitamin D status and risk of schizophrenia
TLDR
Neonatal vitamin D deficiency was associated with an increased risk for schizophrenia in later life, and this findings could have important public health implications related to the primary prevention of schizophrenia. Expand
Minimizing Matrix Effects for the Accurate Quantification of 25-Hydroxyvitamin D Metabolites in Dried Blood Spots by LC-MS/MS.
TLDR
This method to quantify the major circulatory form of vitamin D, 25-hydroxyvitamin D, in archived dried blood spots has performed reliably over the past 6 years and should allow clinical chemists to successfully adapt this method. Expand
Developmental vitamin D and autism spectrum disorders: findings from the Stockholm Youth Cohort
TLDR
The results are consistent with an increasing body of evidence suggesting that vitamin D concentrations in early life may be associated with increased risk of neurodevelopmental disorders including ASD. Expand
Sterol transfer by atypical cholesterol-binding NPC2 proteins in coral-algal symbiosis
TLDR
It is proposed that symbiosis-specific, non-canonical NPCs are adapted to the symbiosome environment, including low pH, and play an important role in allowing corals to dominate nutrient-poor shallow tropical seas worldwide. Expand
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