• Publications
  • Influence
A nomenclature for restriction enzymes, DNA methyltransferases, homing endonucleases and their genes.
A nomenclature is described for restriction endonucleases, DNA methyltransferases, homing endonucleases and related genes and gene products. It provides explicit categories for the many differentExpand
  • 636
  • 49
  • PDF
Hantavirus infections in Europe.
Summary Hantaviruses are enveloped RNA viruses each carried by a specific rodent species. Three hantaviruses, Puumala, Dobrava, and Saaremaa viruses, are known to cause haemorrhagic fever with renalExpand
  • 319
  • 34
Biology of DNA restriction.
Our understanding of the evolution of DNA restriction and modification systems, the control of the expression of the structural genes for the enzymes, and the importance of DNA restriction in theExpand
  • 552
  • 22
A novel method for efficient amplification of whole hepatitis B virus genomes permits rapid functional analysis and reveals deletion mutants in immunosuppressed patients.
Current knowledge of hepatitis B virus (HBV) sequence heterogeneity is based mainly on sequencing of amplified subgenomic HBV fragments. Here, we describe a method which allows sensitiveExpand
  • 450
  • 22
Gene expression analysis of plant host–pathogen interactions by SuperSAGE
The type III restriction endonuclease EcoP15I was used in isolating fragments of 26 bp from defined positions of cDNAs. We call this substantially improved variant to the conventional serial analysisExpand
  • 274
  • 18
  • PDF
Hantavirus in African Wood Mouse, Guinea
Hantaviruses are rodentborne, emerging viruses that cause life-threatening human diseases in Eurasia and the Americas. We detected hantavirus genome sequences in an African wood mouse (HylomyscusExpand
  • 225
  • 18
  • PDF
Hantavirus infections and their prevention.
Hantaviruses are rodent-borne bunyaviruses which cause haemorrhagic fever with renal syndrome and Hantavirus pulmonary syndrome in humans. This review covers the host interactions of the viruses,Expand
  • 194
  • 14
Evidence for Novel Hepaciviruses in Rodents
Hepatitis C virus (HCV) is among the most relevant causes of liver cirrhosis and hepatocellular carcinoma. Research is complicated by a lack of accessible small animal models. The systematicExpand
  • 148
  • 14
  • PDF
Type III restriction endonucleases translocate DNA in a reaction driven by recognition site‐specific ATP hydrolysis.
Type III restriction/modification systems recognize short non‐palindromic sequences, only one strand of which can be methylated. Replication of type III‐modified DNA produces completely unmethylatedExpand
  • 122
  • 13
Human pathogenic hantaviruses and prevention of infection
Hantaviruses are emerging viruses which are hosted by small mammals. When transmitted to humans, they can cause two clinical syndromes, hemorrhagic fever with renal syndrome or hantavirusExpand
  • 125
  • 13