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Breast MR imaging screening in 192 women proved or suspected to be carriers of a breast cancer susceptibility gene: preliminary results.
The accuracy of MR imaging is significantly higher than that of conventional imaging in screening high-risk women and can be caused by an atypical manifestation of hereditary breast cancers at both conventional and MR imaging and by contrast material enhancement associated with hormonal stimulation. Expand
Suppression of the endogenous luteinizing hormone surge by the gonadotrophin-releasing hormone antagonist Cetrorelix during ovarian stimulation.
It is shown that combined treatment with gonadotrophins and the GnRH antagonist Cetrorelix is a promising method for ovarian stimulation in patients who frequently exhibit premature LH surges and therefore fail to complete treatment. Expand
HLA-G polymorphisms and allele frequencies in Caucasians.
HLA-G, a nonclassical class I MHC molecule, is uniquely expressed on extravillous cytotrophoblasts of the maternal-fetal interface and is suggested to be essential for establishment of maternal-fetalExpand
Ascorbic acid (vitamin C) improves the antineoplastic activity of doxorubicin, cisplatin, and paclitaxel in human breast carcinoma cells in vitro.
Vit C both at non-cytotoxic and moderately cytotoxic concentrations improved the cytotoxicity of DOX, DDP, and Tx significantly, and combination effects were partly synergistic and partly additive or subadditive whereas a consistent synergism was found between Vit C and DOX. Expand
Technetium-99m-MIBI scintimammography for suspicious breast lesions.
Scintigraphy with 99mTc-MIBI is extremely sensitive for the detection of primary breast cancer in patients with a palpable mass, however, SPECT did not improve the diagnostic accuracy over planar scintimammography. Expand
Association of soluble HLA-G plasma levels with HLA-G alleles.
It is demonstrated that the generation of sHLA-G molecules is associated to certain HLA-G alleles and imply that sHLa-G levels are under genetic control, which suggests different levels of functionality in immune regulation. Expand
Combined cytogenetic and Y chromosome microdeletion screening in males undergoing intracytoplasmic sperm injection.
Although rare in number, microdeletions of the Y chromosome can also be observed in patients with moderately reduced sperm counts, and a more proximal site of the deletion breakpoint does not necessarily imply a more severe impairment of spermatogenesis than a distal deletion site. Expand
Transvaginal sonography of the endometrium during ovum pickup in stimulated cycles for in vitro fertilization.
It is concluded that the texture of the endometrium at the time of ovum pickup has a prognostic value for the likelihood of implantation to occur. Expand
Accumulation of pollutants in the genital tract of sterility patients.
The results show that considerable concentrations of chlorinated hydrocarbons may be present in parts of the reproductive system, and that these compounds accumulate in the reception zone for spermatozoa. Expand
[TNF-alpha secretion by peritoneal macrophages in endometriosis].
It is found significant higher TNF-alpha-concentrations in the peritoneal fluid of patients with endometriosis than in theperitoneal fluids of healthy women, and there is a correlation between TNF -alpha- Concentrations and the degree of disease. Expand