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Stereotactic radiosurgery plus whole brain radiotherapy versus radiotherapy alone for patients with multiple brain metastases.
The natural history of cerebral cavernous malformations.
It is indicated that conservative versus operative management strategies may need to be redefined, especially in patients who present with hemorrhage and who appear to have a significantly increased risk of subsequent rehemorrhage.
Seizure outcome in children treated for arteriovenous malformations using gamma knife radiosurgery.
- P. Gerszten, P. Adelson, D. Kondziolka, J. Flickinger, L. Lunsford
- MedicinePediatric neurosurgery
It is concluded that stereotactic radiosurgery, as a non-invasive alternative, is associated with a good outcome for the AVM as well as AVM-related seizures in children.
Effects of stereotactic radiosurgery on an animal model of hippocampal epilepsy.
In this rat hippocampal epilepsy model, stereotactic radiosurgery was followed by a significant dose-dependent reduction in the frequency of observed and EEG-defined seizures, which were not accompanied by increased radiation-induced structural or metabolic brain injury as assessed by proton and sodium MRI or histological examination.
Subnecrotic stereotactic radiosurgery controlling epilepsy produced by kainic acid injection in rats.
- S. Maesawa, D. Kondziolka, C. Dixon, J. Balzer, W. Fellows, L. Lunsford
- Medicine, BiologyJournal of neurosurgery
- 1 December 2000
In a rat model, radiosurgery performed with subnecrotic tissue doses controlled epilepsy without causing subsequent behavioral impairment.
A multi-institutional experience with stereotactic radiosurgery for solitary brain metastasis.
The role of stereotactic radiosurgery in the management of patients with newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline
Regular careful surveillance is warranted for patients treated with SRS alone in order to provide early identification of local and distant recurrences so that salvage therapy can be initiated at the soonest possible time.
Long-term outcomes after radiosurgery for acoustic neuromas.
- D. Kondziolka, L. Lunsford, M. R. Mclaughlin, J. Flickinger
- MedicineThe New England journal of medicine
- 12 November 1998
Radiosurgery can provide long-term control of acoustic neuromas while preserving neurologic function and no new neurologic deficits appeared more than 28 months after radiosurgery.
Stereotactic radiosurgery for arteriovenous malformations of the brain.
Stereotactic radiosurgery successfully obliterates carefully selected arteriovenous malformations (AVM's) of the brain, especially those previously considered inoperable, in an initial 3-year experience using the 201-source cobalt-60 gamma knife at the University of Pittsburgh.
Results of acoustic neuroma radiosurgery: an analysis of 5 years' experience using current methods.
Radiosurgery for acoustic neuroma performed using current procedures is associated with a continued high rate of tumor control and lower rates of posttreatment morbidity than those published in earlier reports.