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Biphasic electric current stimulates proliferation and induces VEGF production in osteoblasts.
- I. Kim, J. K. Song, +6 authors S. J. Hwang
- Medicine, Biology
- Biochimica et biophysica acta
- 1 September 2006
This study investigated biphasic electric current (BEC) functions as a new type of electrical stimulation to induce rat calvarial osteoblasts to proliferate, differentiate and synthesize cytokines.… Expand
Interleukin-33 stimulates formation of functional osteoclasts from human CD14+ monocytes
- S. H. Mun, N. Y. Ko, +11 authors W. Choi
- Biology, Medicine
- Cellular and Molecular Life Sciences
- 8 June 2010
Interleukin (IL)-33 is a recently described pro-inflammatory cytokine. Here we demonstrate IL-33 as a regulator of functional osteoclasts (OCs) from human CD14+ monocytes. IL-33 stimulates formation… Expand
Morus bombycis Koidzumi extract suppresses collagen-induced arthritis by inhibiting the activation of nuclear factor-κB and activator protein-1 in mice.
ETHNOPHARMACOLOGICAL RELEVANCE Morus bombycis Koidzumi is widely distributed in Asia. In Korea, it has been used in traditional medicine because of its apparent anti-inflammatory, antioxidant, and… Expand
DJ-1 regulates mast cell activation and IgE-mediated allergic responses.
- D. Kim, H. Kim, +7 authors W. Choi
- Biology, Medicine
- The Journal of allergy and clinical immunology
- 1 June 2013
BACKGROUND DJ-1 is an antioxidant protein known to reduce levels of reactive oxygen species (ROS), but its presence or function in mast cells and allergic diseases is unknown. OBJECTIVES We sought… Expand
Tumor necrosis factor alpha-induced interleukin-32 is positively regulated via the Syk/protein kinase Cdelta/JNK pathway in rheumatoid synovial fibroblasts.
OBJECTIVE Interleukin-32 (IL-32) is a recently discovered cytokine that appears to play a critical role in human rheumatoid arthritis (RA). It is highly expressed in synovium and fibroblast-like… Expand
The Scaffold Protein Prohibitin Is Required for Antigen-Stimulated Signaling in Mast Cells
Targeting a scaffold protein delivered by intracellular granules in mast cells may inhibit allergic responses. How to Prohibit Mast Cell Activation Mast cells are the major effector cells of the… Expand
Oral administration of curcumin suppresses production of matrix metalloproteinase (MMP)-1 and MMP-3 to ameliorate collagen-induced arthritis: inhibition of the PKCdelta/JNK/c-Jun pathway.
We investigated whether oral administration of curcumin suppressed type II collagen-induced arthritis (CIA) in mice and its effect and mechanism on matrix metalloproteinase (MMP)-1 and MMP-3… Expand
Isolation and Culture Properties of a Thermophilic Agarase-Producing Strain, Microbulbifer sp. SD-1
An agar-degrading enzyme-producing strain was isolated from seawater. The isolate was identified as Microbulbifer sp. SD-1 by 16S rRNA sequencing analysis. The optimal pH and temperature for growth… Expand
The Src Family Kinase Fgr Is Critical for Activation of Mast Cells and IgE-Mediated Anaphylaxis in Mice
Mast cells are critical for various allergic disorders. Mast cells express Src family kinases, which relay positive and negative regulatory signals by Ag. Lyn, for example, initiates activating… Expand
Morus bombycis extract suppresses mast cell activation and IgE-mediated allergic reaction in mice.
ETHNOPHARMACOLOGICAL RELEVANCE Morus bombycis Koidzumi (MB) is widely distributed throughout Korea, where it is used as a traditional folk remedy for the treatment of allergic diseases including… Expand