• Publications
  • Influence
The Shigella flexneri effector OspG interferes with innate immune responses by targeting ubiquitin-conjugating enzymes.
Bacteria of Shigella spp. are responsible for shigellosis in humans. They use a type III secretion system to inject effector proteins into host cells and induce their entry into epithelial cells orExpand
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Evidence for several waves of global transmission in the seventh cholera pandemic
Vibrio cholerae is a globally important pathogen that is endemic in many areas of the world and causes 3–5 million reported cases of cholera every year. Historically, there have been sevenExpand
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Comparative genomics reveals mechanism for short-term and long-term clonal transitions in pandemic Vibrio cholerae
  • J. Chun, C. Grim, +20 authors R. Colwell
  • Medicine, Biology
  • Proceedings of the National Academy of Sciences
  • 8 September 2009
Vibrio cholerae, the causative agent of cholera, is a bacterium autochthonous to the aquatic environment, and a serious public health threat. V. cholerae serogroup O1 is responsible for the previousExpand
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An injected bacterial effector targets chromatin access for transcription factor NF-κB to alter transcription of host genes involved in immune responses
Phosphorylation of histone H3 at Ser10 increases chromatin accessibility to transcription factor NF-κB on a subset of genes involved in immune responses. Here we report that a bacterial pathogenExpand
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Radiofrequency Ablation of Benign Thyroid Nodules and Recurrent Thyroid Cancers: Consensus Statement and Recommendations
Thermal ablation using radiofrequency is a new, minimally invasive modality employed as an alternative to surgery in patients with benign thyroid nodules and recurrent thyroid cancers. The Task ForceExpand
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cAMP Response Element-binding Protein-binding Protein Binds to Human Papillomavirus E2 Protein and Activates E2-dependent Transcription*
cAMP response element-binding protein-binding protein (CBP) is a eucaryotic transcriptional co-activator that contains multiple protein-protein interaction domains for association with variousExpand
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An orally administered multitarget tyrosine kinase inhibitor, SU11248, is a novel potent inhibitor of thyroid oncogenic RET/papillary thyroid cancer kinases.
  • D. Kim, Y. Jo, +10 authors M. Shong
  • Medicine
  • The Journal of clinical endocrinology and…
  • 1 October 2006
CONTEXT The oncogenic RET/PTC tyrosine kinase causes papillary thyroid cancer (PTC). The use of inhibitors specific for RET/PTC may be useful for targeted therapy of PTC. OBJECTIVE The objective ofExpand
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Ultrasonography Diagnosis and Imaging-Based Management of Thyroid Nodules: Revised Korean Society of Thyroid Radiology Consensus Statement and Recommendations
The rate of detection of thyroid nodules and carcinomas has increased with the widespread use of ultrasonography (US), which is the mainstay for the detection and risk stratification of thyroidExpand
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Ultrasonography and the Ultrasound-Based Management of Thyroid Nodules: Consensus Statement and Recommendations
The detection of thyroid nodules has become more common with the widespread use of ultrasonography (US). US is the mainstay for detecting and making the differential diagnosis of thyroid nodules asExpand
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Early‐ and Late‐onset Complications of the Ketogenic Diet for Intractable Epilepsy
Summary:  Purpose: This study was undertaken to evaluate the exact limitations of the ketogenic diet (KD) and to collect data on the prevention and management of its risks.
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