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Effect of anaesthesia on the cytokine responses to abdominal surgery.
It is concluded that anaesthesia with alfentanil and propofol diminished release of IL-6 in response to abdominal surgery compared with isoflurane and that this reduction was an effect of alfENTanil. Expand
Hydrogen peroxide in expired breath condensate of patients with acute respiratory failure and with ARDS
High concentrations of H2O2 in breath condensate were only found in patients with ARDS or with risk factors for ARDS, adding to the existing evidence that reactive oxygen species are associated with some acute lung diseases. Expand
Use of modified fluid gelatin and hydroxyethyl starch for colloidal volume replacement in major orthopaedic surgery.
Both colloidal solutions were comparable in volume efficacy and effects on plasma oncotic pressure, clotting and plasma homeostasis, according to a controlled, randomized, single-blind clinical design. Expand
Validation of myocardial oxygen demand indices in patients awake and during anesthesia.
The constants of the PWI and Eg formulas, which have been developed based on animal experiments, therefore are not directly applicable to clinical conditions, have been derived by multiple linear regression analysis of the data in the current investigation. Expand
Effects of propofol on cardiovascular dynamics, myocardial blood flow and myocardial metabolism in patients with coronary artery disease.
Propofol may on occasions, lead to myocardial ischaemia in patients with coronary artery disease, but that it is able to block the sympathetic responses to surgical stimulation when combined with a suitable analgesic. Expand
Endocrinological changes following etomidate, midazolam, or methohexital for minor surgery.
Etomidate had no influence on plasma catecholamines, but midazolam attenuated the stress-related epinephrine increase and ACTH and beta-endorphin levels increased in patients receiving etomidate, presumably as a result of the interruption of negative feedback due to cortisol synthesis inhibition. Expand
Pharmacokinetics of piritramide after an intravenous bolus in surgical patients
Background: Piritramide is a synthetic opioid analgesic which is commonly used for postoperative analgesia. It is structurally related to meperidine, exhibiting full μ‐receptor agonism.Expand
Nausea and vomiting after laparoscopic surgery: a comparison of propofol and thiopentone/halothane anaesthesia.
Patients with propofol anaesthesia had lower emetic scores and higher recovery scores compared with those after thiopentone/halothane anaesthesia. Expand
Cost effectiveness of general anaesthesia: inhalation vs i.v.