Optical coherence tomography helps differentiate neuromyelitis optica and MS optic neuropathies
- J. Ratchford, M. Quigg, D. Kerr
- MedicineNeurology
- 28 July 2009
Optical coherence tomography (OCT) shows more severe retinal damage after optic neuritis (ON) episodes in neuromyelitis optica (NMO) spectrum patients than in relapsing–remitting multiple sclerosis.
High resolution diffusion tensor imaging of axonal damage in focal inflammatory and demyelinating lesions in rat spinal cord.
- C. A. DeBoy, Jiangyang Zhang, P. Calabresi
- Biology, PsychologyBrain : a journal of neurology
- 1 August 2007
High resolution diffusion tensor imaging data suggest that high resolution DTI may be a more sensitive method than conventional imaging for detecting axonal damage at sites distant from inflammation.
Neuromyelitis optica pathogenesis and aquaporin 4
Dysregulation of tolerance associated with autoimmune disease appears to have a role in NMO and reagents and experimental questions that need to be developed and addressed are identified to enhance the understanding of the pathogenesis of NMO.
Recovery from paralysis in adult rats using embryonic stem cells
- D. Deshpande, Y. Kim, D. Kerr
- BiologyAnnals of Neurology
- 1 July 2006
We explored the potential of embryonic stem cell–derived motor neurons to functionally replace those cells destroyed in paralyzed adult rats.
Transverse Myelitis: pathogenesis, diagnosis and treatment.
- C. Krishnan, A. Kaplin, D. Deshpande, C. Pardo, D. Kerr
- MedicineFrontiers in Bioscience
- 1 May 2004
Recent classification and diagnostic schemes are summarized, which provide a framework for the acute management of patients with TM and current concepts on the natural history, immunopathogenesis and treatment strategies for patients withTM are reviewed.
Diagnosis and Management of Acute Myelopathies
- A. Kaplin, C. Krishnan, D. Deshpande, C. Pardo, D. Kerr
- MedicineThe Neurologist
- 1 January 2005
With more rigorous criteria applied to distinguish acute myelopathies and with an emerging understanding of immunopathogenic events that underlie TM, it may now be possible to effectively initiate treatments in many of these disorders.
Acute transverse myelitis in childhood
- F. Pidcock, C. Krishnan, T. Crawford, C. Salorio, M. Trovato, D. Kerr
- MedicineNeurology
- 1 May 2007
Persisting disability was present in many children with acute transverse myelitis and age at onset below 3 years was associated with worse functional outcomes, while older age at time of diagnosis was associatedwith a better functional outcome.
Nusinersen initiated in infants during the presymptomatic stage of spinal muscular atrophy: Interim efficacy and safety results from the Phase 2 NURTURE study
- D. D. De Vivo, E. Bertini, W. Farwell
- MedicineNeuromuscular Disorders
- 12 September 2019
Human Embryonic Germ Cell Derivatives Facilitate Motor Recovery of Rats with Diffuse Motor Neuron Injury
- D. Kerr, J. Lladó, J. Rothstein
- BiologyJournal of Neuroscience
- 15 June 2003
It is concluded that cells derived from human pluripotent stem cells have the capacity to restore neurologic function in animals with diffuse motor neuron disease via enhancement of host neuron survival and function.
Distinct subtypes of myelitis in systemic lupus erythematosus.
- J. Birnbaum, M. Petri, R. Thompson, I. Izbudak, D. Kerr
- Medicine, PsychologyArthritis & Rheumatism
- 1 November 2009
It is indicated that SLE myelitis encapsulates 2 distinct and previously unrecognized syndromes that can be distinguished clinically by gray matter versus white matter findings.
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