D. J. Van der Horst

Publications78
h-index30
Citations3,131
Highly Influential Citations88
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Insect lipids and lipoproteins, and their role in physiological processes.
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Apolipophorin II/I, Apolipoprotein B, Vitellogenin, and Microsomal Triglyceride Transfer Protein Genes Are Derived from a Common Ancestor
TLDR
Data indicate that the genes coding for apoLp-II/I, apoB, VTG, and the MTP large subunit are members of the same multigene superfamily, suggesting an ancestral molecule designed to ensure a pivotal event in the intracellular and extracellular transfer of lipids and liposoluble substances.
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Molecular diversity and evolution of the large lipid transfer protein superfamilys⃞ Published, JLR Papers in Press, December 5, 2006.
TLDR
Comparative research exposes the structural and functional adaptations in animal lipid carriers and brings up novel possibilities for the manipulation of lipid transport.
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Alternative lipid mobilization: The insect shuttle system
TLDR
The functioning of the insect lipoprotein in energy transport during flight activity is intriguingly different, since the TAG-rich mammalian lipoproteins play no role as a carrier of mobilized lipids during exercise and besides, these lipoins are not functioning as a reusable shuttle for lipid transport.
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Lipid transport biochemistry and its role in energy production.
TLDR
The nature and structure of hemolymph lipid transfer particle and the potential role of a recently discovered lipoprotein receptor of the low-density lipop protein receptor family, in lipophorin metabolism and lipid transport is reviewed.
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Adipokinetic hormones of insect: release, signal transduction, and responses.
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An insect homolog of the vertebrate very low density lipoprotein receptor mediates endocytosis of lipophorins.
TLDR
The expression of this receptor in various tissues that internalize circulating lipophorins and its capability to mediate endocytosis of HDLp indicate that this novel member of the LDL receptor family may function as an endocyticlipophorin receptor in vivo.
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Locust flight activity as a model for hormonal regulation of lipid mobilization and transport.
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Insulin-induced translocation of CD36 to the plasma membrane is reversible and shows similarity to that of GLUT4.
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Insect adipokinetic hormones: release and integration of flight energy metabolism.
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