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- J. A. Rumberger, B H Brundage, D. J. Rader, George Kondos
- Mayo Clinic proceedings
- 1999
Coronary artery disease is the No. 1 cause of death in the developed world. Effective means of treatment such as drug therapy to lower cholesterol levels are available, but clinical application to… (More)
Human plasma contains an inhibitor of tissue factor-initiated coagulation known as the lipoprotein-associated coagulation inhibitor (LACI) or also known as the extrinsic pathway inhibitor (EPI). A… (More)
- Laurel A Bastone, M. Reilly, D. J. Rader, Andrea S. Foulkes
- Human heredity
- 2004
Complex diseases such as cardiovascular disease are likely due to the effects of high-order interactions among multiple genes and demographic factors. Therefore, in order to understand their… (More)
- Rajesh Movva, D. J. Rader
- Annales de biologie clinique
- 2008
BACKGROUND
Plasma concentrations of HDL cholesterol (HDL-C) and its major protein component apolipoprotein (Apo) A-I are strongly inversely associated with cardiovascular risk, leading to the concept… (More)
- Carolyn A Cuff, Devashish Kothapalli, +8 authors Ellen Puré
- The Journal of clinical investigation
- 2001
Atherosclerosis causes most acute coronary syndromes and strokes. The pathogenesis of atherosclerosis includes recruitment of inflammatory cells to the vessel wall and activation of vascular cells.… (More)
- Kurt Thomas Barnhart, E. Freeman, +4 authors John E. Nestler
- The Journal of clinical endocrinology and…
- 1999
Dehydroepiandrosterone (DHEA), an androgenic steroid hormone, exhibits an age-related decline. Perimenopausal women have only approximately 50% of peak DHEA levels. Despite limited scientific data,… (More)
- Joyce B. J. van Meurs, Guillaume Paré, +55 authors Kourosh R. Ahmadi
- The American journal of clinical nutrition
- 2013
BACKGROUND
The strong observational association between total homocysteine (tHcy) concentrations and risk of coronary artery disease (CAD) and the null associations in the homocysteine-lowering… (More)
- Tillman Cyrus, Joseph L. Witztum, +4 authors Christiane Funk
- The Journal of clinical investigation
- 1999
Atherosclerosis may be viewed as an inflammatory disease process that includes early oxidative modification of LDLs, leading to foam cell formation. This "oxidation hypothesis" has gained general… (More)
- D. J. Sharp, L A Blinderman, +7 authors D. J. Rader
- Nature
- 1993
The microsomal triglyceride transfer protein (MTP), which catalyses the transport of triglyceride, cholesteryl ester and phospholipid between phospholipid surfaces, is a heterodimer composed of the… (More)
The convergence behavior of Bird’s Direct Simulation Monte Carlo (DSMC) method is explored for nearcontinuum, one-dimensional Fourier flow. An argon-like, hard-sphere gas is confined between two… (More)