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- Publications
- Influence
Responses of 'Bartlett' pear to withholding irrigation, regulated deficit irrigation, and tree spacing
- P. Mitchell, B. V. D. Ende, P. Jerie, D. J. Chalmers
- Biology
- 1989
- 75
- 1
Utilization of the resolvedl-isomer of 2-amino-6-phosphonohexanoic acid (l-AP6) as a selective agonist for a quisqualate-sensitized site in hippocampal CA1 pyramidal neurons
- M. Schulte, R. Roon, D. J. Chalmers, D. Sunter, J. Koerner
- Biology
- Brain Research
- 27 June 1994
Brief exposure of rat hippocampal slices to quisqualic acid (QUIS) sensitizes neurons to depolarization by the α-amino-ω-phosphonate excitatory amino acid (EAA) analogues AP4, AP5 and AP6. These… Expand
Differential actions of 3-(4-chlorophenyl) glutamic acid stereoisomers and l-trans-pyrrolidine-2,4-dicarboxylic acid upon l-homocysteic acid- and l-glutamic acid-induced responses from rat spinal…
- D. J. Chalmers, D. Jane, D. Sunter, G. A. Thompson, J. Watkins
- Chemistry, Medicine
- Neuropharmacology
- 1 December 1995
The four recently synthesized stereoisomers of 3-(4-chlorophenyl) glutamic acid (chlorpheg) were individually examined for their abilities to potentiate depolarizations of neonatal rat motoneurones… Expand
Utilization of the resolved L-isomer of 2-amino-6-phosphonohexanoic acid (L-AP6) as a selective agonist for a quisqualate-sensitized site in hippocampal CA1 pyramidal neurons.
- M. Schulte, R. Roon, D. J. Chalmers, D. Sunter, J. Koerner
- Medicine
- Brain research
- 1994
Brief exposure of rat hippocampal slices to quisqualic acid (QUIS) sensitizes neurons to depolarization by the alpha-amino-omega-phosphonate excitatory amino acid (EAA) analogues AP4, AP5 and AP6.… Expand
Diastereoselective synthesis of all four isomers of 3-(4-chlorophenyl) glutamic acid: identification of the isomers responsible for the potentiation of L-homocysteic acid-evoked depolarizations in…
- D. Jane, D. J. Chalmers, +6 authors J. Watkins
- Chemistry, Medicine
- Journal of medicinal chemistry
- 22 November 1996
All four isomers of 3-(4-chlorophenyl)glutamic acid (5-8) were prepared by diastereoselective synthesis. Addition of (6S)-(+)-bis-lactim ether 15 to cis-4-chlorocinnamate 12 gave a mixture comprising… Expand