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The Atlantic salmon genome provides insights into rediploidization
The whole-genome duplication 80 million years ago of the common ancestor of salmonids (salmonid-specific fourth vertebrate whole-genome duplication, Ss4R) provides unique opportunities to learn aboutExpand
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The melanocortin receptors: agonists, antagonists, and the hormonal control of pigmentation.
Molecular cloning experiments have led to the identification and characterization of a family of five receptors for the melanocortin (melanotropic and adrenocorticotropic) peptides. The first twoExpand
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The role of melanocyte-stimulating hormone (MSH) receptor in bovine coat color determination
The melanocyte-stimulating hormone (MSH) receptor has a major function in the regulation of black (eumelanin) versus red (phaeomelanin) pigment synthesis within melanocytes. We report three allelesExpand
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A non-epistatic interaction of agouti and extension in the fox, Vulpes vulpes
Agouti and extension are two genes that control the production of yellow-red (phaeomelanin) and brown-black (eumelanin) pigments in the mammalian coat1. Extension encodes the melanocyte-stimulatingExpand
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Molecular and pharmacological characterization of dominant black coat color in sheep
Abstract. Dominant black coat color in sheep is predicted to be caused by an allele ED at the extension locus. Recent studies have shown that this gene encodes the melanocyte stimulating hormoneExpand
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Quantitative trait loci affecting clinical mastitis and somatic cell count in dairy cattle
Abstract. Norway has a field recording system for dairy cattle that includes recording of all veterinary treatments on an individual animal basis from 1978 onwards. Application of these data in aExpand
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A primary screen of the bovine genome for quantitative trait loci affecting twinning rate
Abstract. An autosomal genome scan for quantitative trait loci (QTL) affecting twinning rate was carried out in the Norwegian Cattle population. Suggestive QTL were detected on Chromosomes (Chr) 5,Expand
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A ligand-mimetic model for constitutive activation of the melanocortin-1 receptor.
Dark coat color in the mouse and fox results from constitutively activated melanocortin-1 receptors. Receptor mutations in the mouse (E92K, L98P), cow (L99P), fox (C125R), and sheep (D119N) clusterExpand
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A missense mutation in growth differentiation factor 9 (GDF9) is strongly associated with litter size in sheep
BackgroundA genome wide association study for litter size in Norwegian White Sheep (NWS) was conducted using the recently developed ovine 50K SNP chip from Illumina. After genotyping 378 progenyExpand
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Mapping and characterization of the dominant black colour locus in sheep.
Dominant black pigment synthesis in sheep is caused by alterations of the melanocortin-1 receptor (MC1-R) coding sequence. Using five bovine microsatellite markers we have mapped the sheep MC1-R geneExpand
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