• Publications
  • Influence
Scaffolds in tissue engineering bone and cartilage.
  • D. Hutmacher
  • Materials Science, Medicine
  • Biomaterials
  • 15 December 2000
Musculoskeletal tissue, bone and cartilage are under extensive investigation in tissue engineering research. A number of biodegradable and bioresorbable materials, as well as scaffold designs, haveExpand
  • 4,301
  • 106
The return of a forgotten polymer : Polycaprolactone in the 21st century
During the resorbable-polymer-boom of the 1970s and 1980s, polycaprolactone (PCL) was used in the biomaterials field and a number of drug-delivery devices. Its popularity was soon superseded byExpand
  • 2,215
  • 56
Fused deposition modeling of novel scaffold architectures for tissue engineering applications.
Fused deposition modeling, a rapid prototyping technology, was used to produce novel scaffolds with honeycomb-like pattern, fully interconnected channel network, and controllable porosity and channelExpand
  • 1,369
  • 40
Mechanical properties and cell cultural response of polycaprolactone scaffolds designed and fabricated via fused deposition modeling.
A number of different processing techniques have been developed to design and fabricate three-dimensional (3D) scaffolds for tissue-engineering applications. The imperfection of the currentExpand
  • 1,168
  • 27
25th anniversary article: Engineering hydrogels for biofabrication.
With advances in tissue engineering, the possibility of regenerating injured tissue or failing organs has become a realistic prospect for the first time in medical history. Tissue engineering - theExpand
  • 907
  • 26
State of the art and future directions of scaffold‐based bone engineering from a biomaterials perspective
Scaffold‐based bone tissue engineering aims to repair/regenerate bone defects. Such a treatment concept involves seeding autologous osteogenic cells throughout a biodegradable scaffold to create aExpand
  • 760
  • 23
Scaffold design and fabrication technologies for engineering tissues — state of the art and future perspectives
  • D. Hutmacher
  • Materials Science, Medicine
  • Journal of biomaterials science. Polymer edition
  • 1 January 2001
Today, tissue engineers are attempting to engineer virtually every human tissue. Potential tissue-engineered products include cartilage, bone, heart valves, nerves, muscle, bladder, liver, etc.Expand
  • 1,225
  • 21
Dynamics of in vitro polymer degradation of polycaprolactone-based scaffolds: accelerated versus simulated physiological conditions.
The increasing use of biodegradable devices in tissue engineering and regenerative medicine means it is essential to study and understand their degradation behaviour. Accelerated degradation systemsExpand
  • 298
  • 18
Scaffold-based tissue engineering: rationale for computer-aided design and solid free-form fabrication systems.
TLDR
We review the application, advancement and future directions of SFF techniques in the design and creation of scaffolds for use in clinically driven tissue engineering. Expand
  • 961
  • 17
Additive manufacturing of tissues and organs
Additive manufacturing techniques offer the potential to fabricate organized tissue constructs to repair or replace damaged or diseased human tissues and organs. Using these techniques, spatialExpand
  • 819
  • 15
  • PDF