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Toxicity of Select Beta Adrenergic Receptor-Blocking Pharmaceuticals (B-Blockers) on Aquatic Organisms
TLDR
Based on this study and the expected aqueous environmental exposure levels, adverse effects of propranolol to invertebrate populations is unlikely; however, further reproductive studies are need to elucidate the risk to teleosts.
A Theoretical Model for Utilizing Mammalian Pharmacology and Safety Data to Prioritize Potential Impacts of Human Pharmaceuticals to Fish
TLDR
A model has been developed to utilize the information from mammalian pharmacology and toxicology studies to evaluate the potential for chronic receptor mediated responses in fish and to strengthen the applicability of this approach as a viable tool for prioritizing research initiatives that examine the potential impact of pharmaceuticals on fish.
Toxicity of Fipronil and Its Degradation Products to Procambarus sp.: Field and Laboratory Studies
TLDR
Hazard quotient comparisons using measured water concentrations in the field and laboratory-based LC50s indicated that fipronil and its metabolites in water resulting from Icon-treated rice seed planting poses a significant risk to crayfish survival.
Reproductive Assessment of Japanese Medaka (Oryzias latipes) Following a Four-Week Fluoxetine (SSRI) Exposure
TLDR
This study provides novel information on fish biochemical, physiological, and reproduction responses to environmentally realistic fluoxetine concentrations to determine its potential to disrupt teleost reproductive function.
Repeating history: pharmaceuticals in the environment.
Research and resource investments made to understand and assess endocrine-active chemicals can help scientists to define the ecological risks of pharmaceuticals.
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