D. Higuet

Publications41
h-index17
Citations1,020
Highly Influential Citations64
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Dynamics and evolution of trans-posable elements
TLDR
This text presents the evolution of transposable elements (TE) and introduces the analysis of the phylogenies of TEs and their interpretations according to different models, for example, horizontal versus vertical transmission.
Relationships between transposable elements based upon the integrase-transposase domains: Is there a common ancestor?
TLDR
An evolutionary history is proposed that suggests a common ancestor for some integrases and transposases in RNA-mediated elements and DNA-mediated transposable elements.
Survey of genome size in 28 hydrothermal vent species covering 10 families.
TLDR
This is the first broad survey of 2C values in vent organisms and shows that certain hydrothermal vent species have particularly large genomes, including the largest genome yet reported for any anomuran.
Eukaryote DIRS1-like retrotransposons: an overview
TLDR
This study reports 14 new species and 8 new higher taxa that were not previously known to harbor DIRS1-like retrotransposons, which appear widely distributed among eukaryotes, even if they remain undetected in streptophytes and mammals.
corto genetically interacts with Pc-G and trx-G genes and maintains the anterior boundary of Ultrabithorax expression in Drosophila larvae
TLDR
The results provide evidence that corto maintains the anterior border of Ubx expression in third-instar larvae, and suggest that this regulation is accomplished through an interaction with the products of the Pc-G and trx-G genes.
A scenario for the hobo transposable element invasion, deduced from the structure of natural populations of Drosophila melanogaster using tandem TPE repeats.
TLDR
To clarify the dynamics of hobo elements in natural populations, TPE tandem repeats, observed in the polymorphic S region of the element, were used as molecular markers and revealed a geographical distribution which seems to have been stable since the beginning of the 1960s.
MicNeSs: genotyping microsatellite loci from a collection of (NGS) reads
TLDR
An algorithm to automatically and efficiently genotype microsatellites from a collection of reads sorted by individual, which can be used to genotype any microsatellite locus from any organism and has been tested on 454 pyrosequencing data of several loci from fruit flies and red deers.
Expression of lamin A mutated in the carboxyl-terminal tail generates an aberrant nuclear phenotype similar to that observed in cells from patients with Dunnigan-type partial lipodystrophy and…
TLDR
Transfected cells develop similar phenotypes when expressing lamins mutated in the carboxyl-terminal tail at sites responsible for FPLD or EDMD, which is correlated with their variable endogenous content in A-type lamins and emerin.
Expression of a Mutant Lamin A That Causes Emery-Dreifuss Muscular Dystrophy Inhibits In Vitro Differentiation of C2C12 Myoblasts
TLDR
Myoblast-to-myotube differentiation in C2C12 clones overexpressing lamin A mutated at arginine 453 (R453W), one of the most frequent mutations in EDMD, is analyzed to study the pathophysiology of EDMD.
Lack of correlation between dysgenic traits in the hobo system of hybrid dysgenesis in Drosophila melanogaster.
TLDR
The data reveal that molecular and GD sterility tests are not sufficient to classify strains in the hobo system, and that all the components of the dysgenic syndrome must be taken into account.
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