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Pollen-related food allergy: cloning and immunological analysis of isoforms and mutants of Mal d 1, the major apple allergen, and Bet v 1, the major birch pollen allergen
SummaryBackground: Mal d 1, the major apple allergen, cross-reacts with IgE specific for the major birch pollen allergen, Bet v 1, and is responsible for birch pollen related food allergy to apple.Expand
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Involvement of Carbohydrate Epitopes in the IgE Response of Celery–Allergic Patients
Background: This study was performed to get further insights into antibody responses to cross–reactive carbohydrate determinants (CCD), including initial experiments to prove the biological activityExpand
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Development of a functional in vitro assay as a novel tool for the standardization of allergen extracts in the human system
Background:  Biochemical and immunochemical methods used for batch control of allergen extracts rely on the binding of IgE molecules to allergens. They do not measure the ability of a protein toExpand
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Comparison of four variants of a major allergen in hazelnut (Corylus avellana) Cor a 1.04 with the major hazel pollen allergen Cor a 1.01.
The aim of this study was to produce the Bet v 1-related major hazelnut allergen Cor a 1.0401 and variants thereof as recombinant allergens, and to compare their immuno-reactivity with the majorExpand
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Biologic allergen assay for in vivo test allergens with an in vitro model of the murine type I reaction.
BACKGROUND The determination of the biologic activity of allergenic extracts in human beings is limited for ethical and practical reasons. The establishment of a simplified in vitro model, whichExpand
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Cross-reactivity and epitope analysis of Pru a 1, the major cherry allergen.
A high percentage of birch pollen allergic patients experiences food hypersensivity after ingestion of fresh fruits and vegetables. The cross-reactivity of the major allergens of sweet cherry (Pru aExpand
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Factors influencing the quality of food extracts for in vitro and in viio diagnosis
Food extracts for diagnostic purposes often lack sufficient activity and consistency. Biologically standardized food extracts are not available on the market. Using extracts from plant‐derived foodsExpand
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Determination of the allergenic activity of birch pollen and apple prick test solutions by measurement of β‐hexosaminidase release from RBL‐2H3 cells. Comparison with classical methods in allergen
Background: A murine in vitro model of the allergic type I reaction was set up to determine the biologic activity of extracts without involvement of human beings. It is based on β‐hexosaminidaseExpand
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Allergens in raw and roasted hazelnuts (Corylus avellana) and their cross-reactivity to pollen
Abstract Hazelnuts (HNs), widely distributed in sweets, provoke one of the most frequent pollen-associated food allergies. In this study HN allergens were investigated and immunologicallyExpand
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Influence of food processing on the immunochemical stability of celery allergens
Celery roots were processed by microwave heating, cooking, drying, γ-irradiation, ultra high pressure treatment and high voltage impulse treatment. The immunochemical stabilities of the three knownExpand
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