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  • Influence
Molecular cloning.
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Association of Anxiety-Related Traits with a Polymorphism in the Serotonin Transporter Gene Regulatory Region
Transporter-facilitated uptake of serotonin (5-hydroxytryptamine or 5-HT) has been implicated in anxiety in humans and animal models and is the site of action of widely used uptake-inhibitingExpand
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A functional polymorphism in the monoamine oxidase A gene promoter
Abstract We describe a new polymorphism upstream of the gene for monoamine oxidase A (MAOA), an important enzyme in human physiology and behavior. The polymorphism, which is located 1.2 kb upstreamExpand
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Population and familial association between the D4 dopamine receptor gene and measures of Novelty Seeking
Twin and adoption studies suggest that 30 to 60% of the variance in many personality traits is due to inherited factors. However, there is little knowledge of the number or identity of theExpand
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A linkage between DNA markers on the X chromosome and male sexual orientation.
The role of genetics in male sexual orientation was investigated by pedigree and linkage analyses on 114 families of homosexual men. Increased rates of same-sex orientation were found in the maternalExpand
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Evidence for a Gene-Environment Interaction in Predicting Behavioral Inhibition in Middle Childhood
Gene-environment interactions are presumed to shape human behavior during early development. However, no human research has demonstrated that such interactions lead to stable individual differencesExpand
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Association between the serotonin transporter promoter polymorphism and personality traits in a primarily female population sample.
The serotonin transporter (5-HTT) regulates serotonergic neurotransmission and is thought to influence emotion. A 5-HTT-linked polymorphic region (5-HTTLPR) has two common variants, short (s) andExpand
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Overexpression of metallothionein confers resistance to anticancer drugs.
Resistance to antineoplastic agents is the major obstacle to curative therapy of cancer. Tumor cell lines with acquired resistance to the antineoplastic agent cis-diamminedichloroplatinum(II)Expand
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Linkage between sexual orientation and chromosome Xq28 in males but not in females
We have extended our analysis of the role of the long arm of the X chromosome (Xq28) in sexual orientation by DNA linkage analyses of two newly ascertained series of families that contained eitherExpand
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A genomewide scan of male sexual orientation
This is the first report of a full genome scan of sexual orientation in men. A sample of 456 individuals from 146 families with two or more gay brothers was genotyped with 403 microsatellite markersExpand
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