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Defective aeroallergen surveillance by airway mucosal dendritic cells as a determinant of risk for persistent airways hyper-responsiveness in experimental asthma
A hallmark of atopic asthma is development of chronic airways hyper-responsiveness (AHR) that persists in the face of ongoing exposure to perennial aeroallergens. We investigated underlying… Expand
UV inhibits allergic airways disease in mice by reducing effector CD4+ T cells
- J. P. McGlade, D. H. Strickland, +6 authors P. Hart
- Clinical and experimental allergy : journal of…
- 1 May 2010
Background In human asthma, and experimental allergic airways disease in mice, antigen‐presenting cells and CD4+ effector cells at the airway mucosa orchestrate, and CD4+CD25+ regulatory T cells… Expand