D. H. Edwards

Publications91
h-index29
Citations2,770
Highly Influential Citations154
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Fifty years of a command neuron: the neurobiology of escape behavior in the crayfish
Fifty years ago C.A.G. Wiersma established that the giant axons of the crayfish nerve cord drive tail-flip escape responses. The circuitry that includes these giant neurons has now become one of the… Expand
Neuronal Adaptations to Changes in the Social Dominance Status of Crayfish
The effect of superfused serotonin (5-HT; 50 μm) on the synaptic responses of the lateral giant (LG) interneuron in crayfish was found to depend on the social status of the animal. In socially… Expand
The Effect of Social Experience on Serotonergic Modulation of the Escape Circuit of Crayfish
The neuromodulator serotonin has widespread effects in the nervous systems of many animals, often influencing aggression and dominance status. In crayfish, the effect of serotonin on the neural… Expand
Conservation of structure, signaling and pharmacology between two serotonin receptor subtypes from decapod crustaceans, Panulirus interruptus and Procambarus clarkii
SUMMARY Serotonin (5-HT) plays important roles in the maintenance and modulation of neural systems throughout the animal kingdom. The actions of 5-HT have been well characterized for several… Expand
Serotonin, social status and aggression
Serotonin, social status and aggression appear to be linked in many animal species, including humans. The linkages are complex, and, for the most part, details relating the amine to the behavior… Expand
AnimatLab: A 3D graphics environment for neuromechanical simulations
The nervous systems of animals evolved to exert dynamic control of behavior in response to the needs of the animal and changing signals from the environment. To understand the mechanisms of dynamic… Expand
Escape behavior and escape circuit activation in juvenile crayfish during prey–predator interactions
SUMMARY The neural systems that control escape behavior have been studied intensively in several animals, including mollusks, fish and crayfish. Surprisingly little is known, however, about the… Expand
Direct Benefits of Social Dominance in Juvenile Crayfish
Crayfish are known for their innate aggressiveness and willingness to quickly establish dominance relationships among group members. Consequently, the formation of dominance hierarchies and the… Expand
Dual and Opposing Modulatory Effects of Serotonin on Crayfish Lateral Giant Escape Command Neurons
Serotonin modulates afferent synaptic transmission to the lateral giant neurons of crayfish, which are command neurons for escape behavior. Low concentrations, or high concentrations reached… Expand
The neural basis of dominance hierarchy formation in crayfish
Fifty years of study of the nervous system and behavior of crayfish have revealed neural circuits for movements that are similar to those seen during formation of a dominance hierarchy. Given this… Expand
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