D. H. Bos

Publications19
h-index14
Citations652
Highly Influential Citations65
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Revealing the secret lives of cryptic species: Examining the phylogenetic relationships of echinostome parasites in North America.
The recognition of cryptic parasite species has implications for evolutionary and population-based studies of wildlife and human disease. Echinostome trematodes are a widely distributed, species-rich… Expand
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Using models of nucleotide evolution to build phylogenetic trees.
Molecular phylogenetics and its applications are popular and useful tools for making comparative investigations in genetics; however, estimating phylogenetic trees is not always straightforward. Some… Expand
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Evolution by recombination and transspecies polymorphism in the MHC class I gene of Xenopus laevis.
The patterns of major histocompatibility complex (MHC) evolution involve duplications, deletions, and independent divergence of loci during episodes punctuated by natural selection. Major differences… Expand
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Microsatellite mutation rates in the eastern tiger salamander (Ambystoma tigrinum tigrinum) differ 10-fold across loci
Microsatellites are commonly used for mapping and population genetics because of their high heterozygosities and allelic variability (i.e., polymorphism). Microsatellite markers are generally more… Expand
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Inferring Population History and Demography Using Microsatellites, Mitochondrial DNA, and Major Histocompatibility Complex (MHC) Genes
Abstract Microsatellites and mitochondrial DNA (mtDNA) have traditionally been used in population genetics because of their variability and presumed neutrality, whereas genes of the major… Expand
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Natural Selection During Functional Divergence to LMP7 and Proteasome Subunit X (PSMB5) Following Gene Duplication
  • D. H. Bos
  • Biology, Medicine
  • Journal of Molecular Evolution
  • 1 February 2005
The LMP7 and PSMB5 genes were created through an ancient gene duplication event of their ancestral locus. These proteins contain an active site of proteolysis, and LMP7 replaces PSMB5 as a component… Expand
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Molecular characterization of major histocompatibility complex class II alleles in wild tiger salamanders (Ambystoma tigrinum)
Major histocompatibility complex (MHC) class II genes are usually among the most polymorphic in vertebrate genomes because of their critical role (antigen presentation) in immune response. Prior to… Expand
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Analysis of regulatory protease sequences identified through bioinformatic data mining of the Schistosoma mansoni genome
BackgroundNew chemotherapeutic agents against Schistosoma mansoni, an etiological agent of human schistosomiasis, are a priority due to the emerging drug resistance and the inability of current drug… Expand
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Haplotype inference from diploid sequence data: evaluating performance using non-neutral MHC sequences.
The direct sequencing of PCR products from diploid organisms is problematic because of ambiguities associated with phase inference in multi-site heterozygotes. Several molecular methods such as… Expand
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Multiple molecular approaches yield no evidence for sex-determining genes in lake sturgeon (Acipenser fulvescens)
Summary Common DNA-based sexing assays have been widely used for the conservation and management of mammals and birds. However, many fishes do not have genetic sex determination and in those that do,… Expand
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