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Rapid detection and typing of dengue viruses from clinical samples by using reverse transcriptase-polymerase chain reaction.
We report on the development and application of a rapid assay for detecting and typing dengue viruses. Oligonucleotide consensus primers were designed to anneal to any of the four dengue virus typesExpand
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Dengue and dengue hemorrhagic fever.
  • D. Gubler
  • Medicine, Biology
  • Clinical microbiology reviews
  • 1 April 1992
Dengue fever, a very old disease, has reemerged in the past 20 years with an expanded geographic distribution of both the viruses and the mosquito vectors, increased epidemic activity, theExpand
  • 1,379
  • 109
Dengue and dengue hemorrhagic fever.
Hundreds of thousands of dengue cases are reported worldwide each year. Given the difficulty in obtaining full reporting, the actual number of human infections is probably much higher than the numberExpand
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Dengue: a continuing global threat
Dengue fever and dengue haemorrhagic fever are important arthropod-borne viral diseases. Each year, there are ∼50 million dengue infections and ∼500,000 individuals are hospitalized with dengueExpand
  • 1,470
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Origin of the West Nile virus responsible for an outbreak of encephalitis in the northeastern United States.
In late summer 1999, an outbreak of human encephalitis occurred in the northeastern United States that was concurrent with extensive mortality in crows (Corvus species) as well as the deaths ofExpand
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Epidemic dengue/dengue hemorrhagic fever as a public health, social and economic problem in the 21st century.
  • D. Gubler
  • Medicine, Biology
  • Trends in microbiology
  • 1 February 2002
Dengue fever/dengue hemorrhagic fever is now one of the most important public health problems in tropical developing countries and also has major economic and societal consequences.
  • 1,410
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Dengue and Dengue Hemorrhagic Fever
  • D. Gubler
  • Biology, Medicine
  • Clinical Microbiology Reviews
  • 1 July 1998
SUMMARY Dengue fever, a very old disease, has reemerged in the past 20 years with an expanded geographic distribution of both the viruses and the mosquito vectors, increased epidemic activity, theExpand
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Emerging flaviviruses: the spread and resurgence of Japanese encephalitis, West Nile and dengue viruses
Mosquito-borne flaviviruses provide some of the most important examples of emerging and resurging diseases of global significance. Here, we describe three of them: the resurgence of dengue inExpand
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Nipah virus: a recently emergent deadly paramyxovirus.
A paramyxovirus virus termed Nipah virus has been identified as the etiologic agent of an outbreak of severe encephalitis in people with close contact exposure to pigs in Malaysia and Singapore. TheExpand
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