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SLC24A5, a Putative Cation Exchanger, Affects Pigmentation in Zebrafish and Humans
Lighter variations of pigmentation in humans are associated with diminished number, size, and density of melanosomes, the pigmented organelles of melanocytes. Here we show that zebrafish goldenExpand
Developmental regulation of zebrafish MyoD in wild-type, no tail and spadetail embryos.
We describe the isolation of the zebrafish MyoD gene and its expression in wild-type embryos and in two mutants with altered somite development, no tail (ntl) and spadetail (spt). In the wild-typeExpand
Lithium perturbation and goosecoid expression identify a dorsal specification pathway in the pregastrula zebrafish.
The zebrafish dorsoventral axis can first be distinguished at gastrulation, upon formation of the embryonic shield, the site of the organizer. We have asked whether the shield is specified beforeExpand
Simple Methods for Generating and Detecting Locus-Specific Mutations Induced with TALENs in the Zebrafish Genome
The zebrafish is a powerful experimental system for uncovering gene function in vertebrate organisms. Nevertheless, studies in the zebrafish have been limited by the approaches available forExpand
Headwaters of the zebrafish — emergence of a new model vertebrate
The understanding of vertebrate development has advanced considerably in recent years, primarily due to the study of a few model organisms. The zebrafish, the newest of these models, has risen toExpand
The zebrafish gene cloche acts upstream of a flk-1 homologue to regulate endothelial cell differentiation.
The zebrafish cloche mutation affects both the endothelial and hematopoietic lineages at a very early stage (Stainier, D. Y. R., Weinstein, B. M., Detrich, H. W., Zon, L. I. and Fishman, M. C.Expand
Selenoprotein N is required for ryanodine receptor calcium release channel activity in human and zebrafish muscle
Mutations affecting the seemingly unrelated gene products, SepN1, a selenoprotein of unknown function, and RyR1, the major component of the ryanodine receptor intracellular calcium release channel,Expand
Efficient identification of TALEN‐mediated genome modifications using heteroduplex mobility assays
The heteroduplex mobility assay (HMA) is widely used to characterize strain variants of human viruses. To determine whether it can detect small sequence differences in homologous templates, weExpand
Delta-mediated specification of midline cell fates in zebrafish embryos
BACKGROUND Fate mapping studies have shown that progenitor cells of three vertebrate embryonic midline structures - the floorplate in the ventral neural tube, the notochord and the dorsal endoderm -Expand
An interacting network of T-box genes directs gene expression and fate in the zebrafish mesoderm
T-box genes encode transcription factors that play critical roles in generating the vertebrate body plan. In many developmental fields, multiple T-box genes are expressed in overlapping domains,Expand