Author pages are created from data sourced from our academic publisher partnerships and public sources.
- Publications
- Influence
Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines
- C. Théry, K. Witwer, +379 authors E. Zuba-Surma
- Chemistry, Medicine
- Journal of extracellular vesicles
- 23 November 2018
TLDR
Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes.
- Bow J. Tauro, D. Greening, +4 authors R. Simpson
- Biology, Medicine
- Methods
- 1 February 2012
Exosomes are 40-100nm extracellular vesicles that are released from a multitude of cell types, and perform diverse cellular functions including intercellular communication, antigen presentation, and… Expand
Two Distinct Populations of Exosomes Are Released from LIM1863 Colon Carcinoma Cell-derived Organoids*
- Bow J. Tauro, D. Greening, Rommel A Mathias, S. Mathivanan, H. Ji, R. Simpson
- Biology, Medicine
- Molecular & Cellular Proteomics
- 10 December 2012
Exosomes are naturally occurring biological nanomembranous vesicles (∼40 to 100 nm) of endocytic origin that are released from diverse cell types into the extracellular space. They have pleiotropic… Expand
Extracellular vesicle isolation and characterization: toward clinical application.
- Rong Xu, D. Greening, H. Zhu, N. Takahashi, R. Simpson
- Biology, Medicine
- The Journal of clinical investigation
- 1 April 2016
Two broad categories of extracellular vesicles (EVs), exosomes and shed microvesicles (sMVs), which differ in size distribution as well as protein and RNA profiles, have been described. EVs are known… Expand
Extracellular vesicles in cancer — implications for future improvements in cancer care
- R. Xu, Alin Rai, Maoshan Chen, Wittaya Suwakulsiri, D. Greening, R. Simpson
- Medicine
- Nature Reviews Clinical Oncology
- 1 October 2018
The sustained growth, invasion, and metastasis of cancer cells depend upon bidirectional cell–cell communication within complex tissue environments. Such communication predominantly involves the… Expand
A protocol for exosome isolation and characterization: evaluation of ultracentrifugation, density-gradient separation, and immunoaffinity capture methods.
- D. Greening, Rong Xu, H. Ji, Bow J. Tauro, R. Simpson
- Biology, Medicine
- Methods in molecular biology
- 2015
Exosomes are 40-150 nm extracellular vesicles that are released from a multitude of cell types, and perform diverse cellular functions including intercellular communication, antigen presentation, and… Expand
Deep Sequencing of RNA from Three Different Extracellular Vesicle (EV) Subtypes Released from the Human LIM1863 Colon Cancer Cell Line Uncovers Distinct Mirna-Enrichment Signatures
- H. Ji, Maoshan Chen, +4 authors R. Simpson
- Biology, Medicine
- PloS one
- 17 October 2014
Secreted microRNAs (miRNAs) enclosed within extracellular vesicles (EVs) play a pivotal role in intercellular communication by regulating recipient cell gene expression and affecting target cell… Expand
Oncogenic H-Ras Reprograms Madin-Darby Canine Kidney (MDCK) Cell-derived Exosomal Proteins Following Epithelial-Mesenchymal Transition*
- Bow J. Tauro, Rommel A Mathias, +11 authors R. Simpson
- Biology, Medicine
- Molecular & Cellular Proteomics
- 3 May 2013
Epithelial-mesenchymal transition (EMT) is a highly conserved morphogenic process defined by the loss of epithelial characteristics and the acquisition of a mesenchymal phenotype. EMT is associated… Expand
EVpedia: a community web portal for extracellular vesicles research
- D. Kim, Jaewook Lee, +92 authors Y. S. Gho
- Computer Science, Medicine
- Bioinform.
- 15 March 2015
TLDR
Emerging roles of exosomes during epithelial-mesenchymal transition and cancer progression.
- D. Greening, Shashi K. Gopal, +4 authors R. Simpson
- Biology, Medicine
- Seminars in cell & developmental biology
- 1 April 2015
Epithelial-mesenchymal transition (EMT) is a highly conserved process defined by the loss of epithelial characteristics, and acquisition of the mesenchymal phenotype. In addition to its central role… Expand