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Dietary intake of stearidonic acid-enriched soybean oil increases the omega-3 index: randomized, double-blind clinical study of efficacy and safety.
TLDR
SDA-enriched soybean oil is a land-based n-3 fatty acid that is a sustainable approach to increasing tissue concentrations of long-chain polyunsaturated n- 3 fatty acids.
Stearidonic Acid-Enriched Soybean Oil Increased the Omega-3 Index, an Emerging Cardiovascular Risk Marker
TLDR
Since EPA supplementation has been shown to raise the Omega-3 index and to lower risk for cardiac events, SDA-SBO may be a viable plant-based alternative for providing meaningful intakes of cardioprotective omega-3 FAs.
A prospective observational study of the clinical toxicology of glyphosate-containing herbicides in adults with acute self-poisoning
TLDR
This prospective observational case series was conducted in two hospitals in Sri Lanka between 2002 and 2007 and found that despite treatment in rural hospitals with limited resources, the mortality was 3.2%, which is lower than that reported in previous case series.
A Phamacoeconomic Analysis of Personalized Dosing vs Fixed Dosing of Pembrolizumab in Firstline PD-L1-Positive Non–Small Cell Lung Cancer
TLDR
Personalized dosing of pembrolizumab may have the potential to save approximately $0.825 billion annually in the United States, likely without impacting outcomes, and should be considered for the firstline management of PD-L1-positive advanced lung cancer.
Cost-Effectiveness of Immune Checkpoint Inhibition in BRAF Wild-Type Advanced Melanoma.
TLDR
For patients with treatment-naive BRAF wild-type advanced melanoma, first-line PEM every 3 weeks followed by second-line IPI or first- line NIVO followed bySecond- line IPI are the most cost-effective, immune-based treatment strategies for metastatic melanoma.
A global comparison of the cost of patented cancer drugs in relation to global differences in wealth.
TLDR
Comparisons of patterns of affordability of cancer drugs in Australia, China, India, Israel, South Africa, the United Kingdom, and the United States show that cancer drugs are less affordable in middle- income countries than in high-income countries.
Glyphosate and aminomethylphosphonic acid are not detectable in human milk.
TLDR
Evidence is provided that glyphosate and AMPA are not detectable in milk produced by women living in this region of the US Pacific Northwest and the results suggest that dietary glyphosate exposure is not a health concern for breastfed infants.
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