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- Publications
- Influence
Structural disorder of monomeric α-synuclein persists in mammalian cells
- François-Xavier Theillet, A. Binolfi, +8 authors Philipp Selenko
- Chemistry, Medicine
- Nature
- 4 February 2016
Intracellular aggregation of the human amyloid protein α-synuclein is causally linked to Parkinson’s disease. While the isolated protein is intrinsically disordered, its native structure in mammalian… Expand
Regulation of RNA processing and transport by a nuclear guanine nucleotide release protein and members of the Ras superfamily.
- T. Kadowaki, D. Goldfarb, L. Spitz, A. Tartakoff, M. Ohno
- Biology, Medicine
- The EMBO journal
- 1 July 1993
The RCC1 gene of mammals encodes a guanine nucleotide release protein (GNRP). RCC1 and a homolog in Saccharomyces cerevisiae (MTR1/PRP20/SRM1) have previously been implicated in control of mRNA… Expand
Gadolinium tagging for high-precision measurements of 6 nm distances in protein assemblies by EPR.
- H. Yagi, D. Banerjee, B. Graham, T. Huber, D. Goldfarb, G. Otting
- Chemistry, Medicine
- Journal of the American Chemical Society
- 16 June 2011
Double electron-electron resonance (DEER) distance measurements of a protein complex tagged with two Gd(3+) chelates developed for rigid positioning of the metal ion are shown to deliver… Expand
Gd3+ complexes as potential spin labels for high field pulsed EPR distance measurements.
- A. Raitsimring, C. Gunanathan, +4 authors D. Goldfarb
- Chemistry, Medicine
- Journal of the American Chemical Society
- 27 October 2007
Pulse electron−electron double resonance distance measurements between two high spin Gd3+ ions in a novel bis-Gd3+ complex involving two pyridine-based gadolinium tetracarboxylate systems linked by a… Expand
Utilizing ESEEM spectroscopy to locate the position of specific regions of membrane-active peptides within model membranes.
- R. Carmieli, N. Papo, H. Zimmermann, A. Potapov, Y. Shai, D. Goldfarb
- Chemistry, Medicine
- Biophysical journal
- 15 January 2006
Membrane-active peptides participate in many cellular processes, and therefore knowledge of their mode of interaction with phospholipids is essential for understanding their biological function. Here… Expand
W-band orientation selective DEER measurements on a Gd3+/nitroxide mixed-labeled protein dimer with a dual mode cavity.
- I. Kaminker, I. Tkach, +5 authors D. Goldfarb
- Chemistry, Medicine
- Journal of magnetic resonance
- 1 February 2013
Double electron-electron resonance (DEER) at W-band (95 GHz) was applied to measure the distance between a pair of nitroxide and Gd(3+) chelate spin labels, about 6 nm apart, in a homodimer of the… Expand
Nanometer-scale distance measurements in proteins using Gd3+ spin labeling.
- A. Potapov, H. Yagi, +4 authors D. Goldfarb
- Chemistry, Medicine
- Journal of the American Chemical Society
- 10 June 2010
Methods for measuring nanometer-scale distances between specific sites in proteins are essential for analysis of their structure and function. In this work we introduce Gd(3+) spin labeling for… Expand
HYSCORE and DEER with an upgraded 95GHz pulse EPR spectrometer.
- D. Goldfarb, Y. Lipkin, +5 authors I. Kaminker
- Chemistry, Medicine
- Journal of magnetic resonance
- 1 September 2008
The set-up of a new microwave bridge for a 95 GHz pulse EPR spectrometer is described. The virtues of the bridge are its simple and flexible design and its relatively high output power (0.7 W) that… Expand
Spectroscopic selection of distance measurements in a protein dimer with mixed nitroxide and Gd3+ spin labels.
- I. Kaminker, H. Yagi, T. Huber, A. Feintuch, G. Otting, D. Goldfarb
- Chemistry, Medicine
- Physical chemistry chemical physics : PCCP
- 7 March 2012
The pulse DEER (Double Electron-Electron Resonance) technique is frequently applied for measuring nanometer distances between specific sites in biological macromolecules. In this work we extend the… Expand
Dynamic Nuclear Polarization in the solid state: a transition between the cross effect and the solid effect.
- D. Shimon, Y. Hovav, A. Feintuch, D. Goldfarb, S. Vega
- Chemistry, Medicine
- Physical chemistry chemical physics : PCCP
- 28 March 2012
Proton Dynamic Nuclear Polarization (DNP) experiments were conducted on a 3.4 T homebuilt hybrid pulsed-EPR-NMR spectrometer, on static samples containing 10 mM or 40 mM TEMPOL in frozen glassy… Expand