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Altered muscarinic receptor subtype expression and functional responses in cyclophosphamide induced cystitis in rats
In the in vitro study, it was investigated whether the expression of muscarinic receptors and cholinergic responses were altered in the situation of experimental cystitis. Rats were treated withExpand
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Muscarinic receptor subtypes in the alimentary tract.
Acetylcholine is a transmitter in preganglionic autonomic and postganglionic parasympathetic nerves and a non-neuronal paracrine mediator in the alimentary tract. Acetylcholine is involved in theExpand
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Cholinergic nitric oxide release from the urinary bladder mucosa in cyclophosphamide‐induced cystitis of the anaesthetized rat
Background and purpose: Previous reports have suggested that nitric oxide (NO) may be released by cholinergic stimuli in the rat bladder in cyclophosphamide‐induced cystitis, affecting bladderExpand
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Studies of muscarinic receptor subtypes in salivary gland function in anaesthetized rats
The in vivo study aimed to examine whether muscarinic receptor subtypes other than muscarinic M3 receptors exert exocrine functional roles in the rat salivary glands. The effects of pirenzepine,Expand
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On the functional role of muscarinic M2 receptors in cholinergic and purinergic responses in the rat urinary bladder.
The functional effects of muscarinic receptor and purinoceptor agonists and antagonists were studied on isolated strip preparations of the rat urinary bladder. The muscarinic "M3/M1-selective"Expand
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Assessment and characterization of purinergic contractions and relaxations in the rat urinary bladder.
The aim of the present study was to assess the purinoceptor functional responses of the urinary bladder by using isolated rat urinary bladder strip preparations. ATP elicited a transient bladderExpand
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Muscarinic Receptor Subtypes in the Lower Urinary Tract
Acetylcholine acting on muscarinic M3 receptors on the detrusor muscle is the principal stimulus for inducing the contractile response for urinary bladder voiding. The urinary bladder expresses,Expand
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Potentially Malignant Oral Disorders and Cancer Transformation
Cancer in the oral cavity is often preceded by precursor lesions. Nine oral mucosal disorders are known to have an increased risk of malignant transformation. The etiology varies from disordersExpand
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Radiation induces changes in toll-like receptors of the uterine cervix of the rat
Radiotherapy is an important therapeutic approach against cervical cancer but associated with adverse effects including vaginal fibrosis and dyspareunia. We here assessed the immunological andExpand
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In vitro characterization of parasympathetic and sympathetic responses in cyclophosphamide-induced cystitis in the rat.
In cyclophosphamide-induced cystitis in the rat, detrusor function is impaired and the expression and effects of muscarinic receptors altered. Whether or not the neuronal transmission may be affectedExpand
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