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Obsessive–compulsive disorder: an integrative genetic and neurobiological perspective
- D. Pauls, A. Abramovitch, S. Rauch, D. Geller
- Psychology, BiologyNature Reviews Neuroscience
- 1 June 2014
Genetic studies indicate that genes affecting the serotonergic, dopaminergic and glutamatergic systems, and the interaction between them, play a crucial part in the functioning of this circuit.
Is juvenile obsessive-compulsive disorder a developmental subtype of the disorder? A review of the pediatric literature.
- D. Geller, J. Biederman, B. Coffey
- PsychologyJournal of the American Academy of Child and…
- 1 April 1998
It is suggested that juvenile OCD may be a developmental subtype of the disorder, and the importance of considering age at onset in clinical and research studies of adults with OCD is stressed.
Developmental Aspects of Obsessive Compulsive Disorder: Findings in Children, Adolescents, and Adults
Findings support a hypothesis of developmental discontinuity between juvenile and adult OCD and identify age specific correlates of the disorder across the life cycle and validate whether juvenile-onset OCD represents a true developmental subtype of the Disorder.
Which SSRI? A meta-analysis of pharmacotherapy trials in pediatric obsessive-compulsive disorder.
- D. Geller, J. Biederman, S. Faraone
- Psychology, MedicineThe American journal of psychiatry
- 1 November 2003
A meta-analysis of published randomized, controlled medication trials in children and adolescents with obsessive-compulsive disorder showed that clomipramine was significantly superior to each of theSSRIs but that the SSRIs were comparably effective.
Long‐term outcome of pediatric obsessive–compulsive disorder: a meta‐analysis and qualitative review of the literature
To review the extant literature on the long‐term outcome of child/adolescent‐onset obsessive–compulsive disorder (OCD), the aim was to establish a smoking cessation strategy for adolescents with OCD.
Disentangling chronological age from age of onset in children and adolescents with obsessive--compulsive disorder.
Considering the heterogeneity of OCD, age at onset may help identify meaningful developmental subtypes of the disorder beyond chronological age and predict different patterns of comorbidity and dysfunction in children and adolescents with OCD.
Obsessive‐Compulsive Disorder in Children and Adolescents: A Review
- D. Geller, J. Biederman, Janice Jones, Stephanie Shapiro, S. Schwartz, Kenneth S. Park
- PsychologyHarvard review of psychiatry
- 1 January 1998
It is suggested that OCD has a bimodal incidence pattern, with one peak of onset at approximately 10 years of age and another during adulthood, and that the juvenile and adult forms are equally prevalent.
Should the diagnosis of Attention-Deficit/ Hyperactivity disorder be considered in children with Pervasive Developmental Disorder?
Results suggest that children with PDD with concomitant symptoms of inattention, hyperactivity and impulsivity may have true comorbid ADHD, and challenge the exclusionary criteria for the diagnosis of ADHD in PDD youth.
Obsessive-compulsive and spectrum disorders in children and adolescents.
- D. Geller
- PsychologyThe Psychiatric clinics of North America
- 1 June 2006
Fluoxetine treatment for obsessive-compulsive disorder in children and adolescents: a placebo-controlled clinical trial.
- D. Geller, S. Hoog, J. G. Jacobson
- Psychology, MedicineJournal of the American Academy of Child and…
- 1 July 2001
Fluoxetine 20 to 60 mg daily was effective and well tolerated for treatment of OCD in this pediatric population of child and adolescent obsessive-compulsive disorder.