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Histopathologic evidence that sacroiliitis in ankylosing spondylitis is not merely enthesitis.
OBJECTIVE To systematically study the histopathology of sacroiliitis in ankylosing spondylitis (AS) at 5 different stages of the disease. METHODS Two independent observers assessed 75 microscopicExpand
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In vitro measurement of articular cartilage deformations in the intact human hip joint under load.
Using a new roentgenographic technique for measuring cartilage deformation in intact joint specimens, twenty-eight normal human hip joints from subjects twenty-five to eighty-five years old wereExpand
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Differential response to compressive loads of zones of canine hyaline articular cartilage: micromechanical, light and electron microscopic studies.
Thin (100 micron) perpendicular slices of canine femoral condylar cartilage were placed horizontally on the stage of a Nachet microscope and viewed by transmitted light in the differentialExpand
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Sacral and iliac articular cartilage thickness and cellularity: relationship to subchondral bone end-plate thickness and cancellous bone density.
OBJECTIVES To measure the thickness and cellularity of adult human sacral and iliac articular cartilages and the thickness and density of the subchondral bones. METHODS The right sacroiliac jointsExpand
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Anisotropic response of the human knee joint meniscus to unconfined compression
Abstract The response of meniscal tissue to axial, radial and circumferential compressive forces was measured at physiologically relevant levels of load in eight pairs of human knee joint menisci.Expand
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Changes with age in the glycosaminoglycans of human articular cartilage.
Human articular cartilage was obtained post mortem from the lateral femoral condyles of 30 subjects aged from under 1 to 70 years. Cryostat sections taken 0--100 micrometers and 900--100 micrometersExpand
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Hyaluronate in rheumatology and orthopaedics: is there a role?
The clinical use of connective tissue substitutes is controversial. This viewpoint aims at outlining and highlighting some of the notable work in the field and at encouraging debate. Hyaluronate is aExpand
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Changes in the deformational behavior of human hip cartilage with age.
The deformation occurring in the articular cartilage covering the human femoral head has been measured both when the femoral head is loaded in its natural acetabulum and when the cartilage is loadedExpand
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Thickness and distribution of human femoral head articular cartilage. Changes with age.
The distribution of hyaline cartilage in the sagittal plane of the normal human femoral head was examined. 28 specimens from persons aged 10 to 68 years subject to post-mortem examination in aExpand
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Intra-articular hyaluronate in experimental rabbit osteoarthritis can prevent changes in cartilage proteoglycan content.
OBJECTIVE The purpose of this study was to determine the effects of intra-articular injections of high molecular weight (2000 kDa) sodium hyaluronate (HA) on the progression of articular cartilageExpand
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